Simple vitamin pills could cut blood transfusions in pregnant african women
NCT ID NCT00148629
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether adding daily multivitamins and an extra dose of deworming medication to standard prenatal care could prevent severe anemia in pregnant women in Zanzibar, Tanzania. Over 2,500 pregnant women took part, comparing the enhanced package to the usual WHO-recommended care. The goal was to reduce the need for blood transfusions and improve health for both mothers and babies.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- multivitamin and mebendazole (deworming drug)
- What this could lead to
- If successful, this could offer a simple, low-cost way to prevent severe anemia in pregnant women in resource-limited settings, reducing the need for blood transfusions and improving birth outcomes.
- What could go wrong
- This trial is completed but results may not apply to other regions or populations. The interventions are low-cost and low-risk, but the benefit may be modest compared to standard care alone.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 3
Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.
- Participants
-
2,500 people
- Started
-
Apr 2004
- Finished
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Jan 2008
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Female participants only
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Pregnant woman Exclusion Criteria: * Not a permanent resident of the community
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Public Health Laboratory "Ivo de Carneri"
Wawi, Zanzibar, Tanzania
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Other studies related to the condition(s) this trial covers.
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