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New combo therapy shows promise for rare bone marrow disorder

NCT ID NCT05399732

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 33 times

Summary

This study tested whether adding luspatercept to standard cyclosporine treatment helps people with newly diagnosed non-severe aplastic anemia (a rare bone marrow failure condition) who do not yet need blood transfusions. The trial enrolled 58 adults and compared the combination therapy to cyclosporine alone. The main goal was to see if the combination improved blood counts and reduced symptoms like fatigue and risk of infection.

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Contacts and locations

Locations

  • Peking union medical college hospital

    Beijing, China

Conditions

Explore the condition pages connected to this study.