Can a computer program tame sickle cell pain crises?
NCT ID NCT00600665
First seen Aug 04, 2026 · Last updated Aug 05, 2026 · Updated 1 time
Summary
This trial tests a computer-based tool called PAINRelieveIt for adults with sickle cell disease, a condition that causes intense pain episodes. The tool has three parts: one helps patients report their pain, another educates them about pain management, and a third helps doctors choose the right pain medication. The study will see if using this tool improves pain control, reduces time in pain crisis, and improves how well patients stick to their pain medication plans.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- PAINRelieveIt, a three-part computer-based pain management tool including PAINReportIt (pain assessment), PAINUCope (patient education), and PAINConsultN (decision support for doctors)
- What this could lead to
- If effective, this tool could help adults with sickle cell disease better manage pain, improve medication adherence, and reduce time spent in pain crises.
- What could go wrong
- This is a behavioral intervention, so results may vary. The trial is not a drug test, and its success depends on how well patients and doctors use the tool in real life.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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279 people
The number who actually took part.
- Start date
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Feb 2007
- Finished
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Jun 2014
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Diagnosed with SCD * Scheduled for continuing care at the University of Illinois at Chicago Sickle Cell Clinic * Experienced a moderate to severe level of pain (at least 3 on 0 to 10 scale) related to the SCD within the 12 months prior to study entry * Had a emergency department visit or hospitalization within the 2 years prior to study entry * Speaks and reads English Exclusion Criteria: * Legally blind * Physically unable to complete study questionnaire
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Illinois at Chicago Sickle Cell Center and Medical Center
Chicago, Illinois, 60612, United States
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