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New combo therapy boosts blood counts in severe anemia patients

NCT ID NCT04328727

First seen Jan 22, 2026 · Last updated May 23, 2026 · Updated 23 times

Summary

This study tested whether adding eltrombopag to standard treatment (anti-thymocyte globulin and cyclosporine) helps East-Asian patients with severe aplastic anemia, a condition where the bone marrow fails to produce enough blood cells. 36 adults and children received the combination therapy. The main goal was to see how many achieved normal blood cell counts by 26 weeks. The approach aims to control the disease, not cure it, as patients may need ongoing medication.

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Contacts and locations

Locations

  • Novartis Investigative Site

    Guangzhou, Guangdong, 510000, China

  • Novartis Investigative Site

    Zhengzhou, Henan, 450052, China

  • Novartis Investigative Site

    Nanchang, Jiangxi, 330006, China

  • Novartis Investigative Site

    Changchun, Jilin, 130021, China

  • Novartis Investigative Site

    Tianjin, 300020, China

  • Novartis Investigative Site

    Tianjin, 300052, China

  • Novartis Investigative Site

    Nagoya, Aichi-ken, 466 8560, Japan

  • Novartis Investigative Site

    Fukuoka, Fukuoka, 812-8582, Japan

  • Novartis Investigative Site

    Chuo Ku, Tokyo, 104 8560, Japan

  • Novartis Investigative Site

    Seoul, 03080, South Korea

  • Novartis Investigative Site

    Seoul, 06351, South Korea

  • Novartis Investigative Site

    Kaohsiung City, 83301, Taiwan

Conditions

Explore the condition pages connected to this study.