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Iron fix: new study tests best way to boost energy in women with hidden deficiency

NCT ID NCT06437080

Disease control Sponsor: Akram Medical Complex Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jul 22, 2026 · Updated 3 times

Summary

This study looked at 1331 women aged 18-45 who had low iron stores but normal hemoglobin (no anemia). They were split into three groups: one got daily oral iron pills for 3 months, another got three IV iron infusions over 3 months, and a third got no treatment. The goal was to see which approach raised iron levels and eased symptoms like fatigue and poor concentration after 4 months.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Iron (oral iron III hydroxide polymaltose complex or IV ferric carboxymaltose)
What this could lead to
If successful, this could show that iron supplements improve symptoms like fatigue and brain fog in women with low iron but normal blood counts.
What could go wrong
This is a completed trial, but results may not apply to all women. Oral iron can cause stomach upset, and IV iron carries rare allergy risks.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

300 people

The number who actually took part.

Started

Oct 2022

Finished

Oct 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 45 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Reproductive age females: 18 to 45 years * Clinical symptoms of iron deficiency which are fatigue/ tiredness, poor work productivity, poor attention and memory loss, sore tongue, poor condition of skin, nails or hair, including hair loss, delayed skin wound healing, palpitation and restless leg syndrome * Normal CBC: hemoglobin level12mg/dl and above * Serum ferritin levels: below 30 ng/ml * Normal thyroid levels * Normal blood sugar levels * Willing and able to sign informed consent Exclusion Criteria: * Males * Post-menopausal * Premature menopause * Anemic Females: hemoglobin levels i.e. less than 12 g/dl * Serum ferritin level above 30 ng/ml. * Disturbed thyroid levels * Disturbed blood sugar levels * Pregnant * Lactating * Blood donors * Co-morbidities i.e., celiac disease, hemorrhoids, malignancies, hematuria, ulcers, heart failure, renal failure, chronic gastric symptoms/ gastric ulcers, chronic liver disease, disturbed thyroid levels and diabetes * Any medication or supplement which may impact iron metabolism. * History of iron or multivitamins supplementation in the last 3 months

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Conditions

The condition(s) this trial relates to.

Iron Deficiencies iron deficiency anemia L-ferritin deficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hypoferritenemia without anemia (HWA) Iron deficiency without anemia)

Contacts and locations

Locations

  • Fatima Memorial Hospital

    Lahore, Punjab Province, 54782, Pakistan

  • General Hospital Lahore

    Lahore, Punjab Province, 54782, Pakistan

  • Gulab Devi Hospital

    Lahore, Punjab Province, 54782, Pakistan

  • Sir Gangaram Hospital

    Lahore, Punjab Province, 54782, Pakistan

More trials for these conditions

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