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New hope for kidney patients: experimental anemia drug shows promise

NCT ID NCT05745883

First seen Jan 11, 2026 · Last updated Jun 19, 2026 · Updated 29 times

Summary

This study tested a new drug called DISC-0974 in 55 adults with chronic kidney disease (not on dialysis) who also have anemia. The goal was to check the drug's safety and how the body processes it. Participants received either the drug or a placebo by injection. The results will help decide if larger studies are warranted.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Accel Research

    DeLand, Florida, 32720, United States

  • CARE Institute - Boise Kidney

    Boise, Idaho, 83706, United States

  • Center for Advanced Kidney Research PLC

    Saint Clair Shores, Michigan, 48081, United States

  • Centricity Research

    Columbus, Ohio, 43213, United States

  • Clinical Advancement Center, PLLC

    San Antonio, Texas, 78212, United States

  • Endeavor Clinical Trials

    San Antonio, Texas, 78240, United States

  • Flourish Research

    Winter Park, Florida, 32789, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Nephrology and Hypertension Specialists, PC-Dalton

    Dalton, Georgia, 30720, United States

  • Total Research Group

    Miami, Florida, 33126, United States

  • UCLA Clinical and Translational Research

    Los Angeles, California, 90095, United States

  • US Renal Care Inc.

    Lone Tree, Colorado, 80124, United States

  • Washington Nephrology Associates, LLP

    Alexandria, Virginia, 22304, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

DISC-0974

What this could lead to

If successful, this could lead to a new treatment option for anemia in people with chronic kidney disease who are not on dialysis.

What could go wrong

This is an early Phase 1b study with only 55 participants, so results may not apply to everyone. The drug may cause side effects or not improve anemia significantly.

Conditions

The condition(s) this trial relates to.

anemia anemia due to chronic disorder chronic kidney disease chronic renal failure syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.