New hope for kidney patients: experimental anemia drug shows promise

NCT ID NCT05745883

Completed Disease control Sponsor: Disc Medicine, Inc Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new drug called DISC-0974 in 55 adults with chronic kidney disease (not on dialysis) who also have anemia. The goal was to check the drug's safety and how the body processes it. Participants received either the drug or a placebo by injection. The results will help decide if larger studies are warranted.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: DISC-0974
What this could lead to: If successful, this could lead to a new treatment option for anemia in people with chronic kidney disease who are not on dialysis.
What could go wrong: This is an early Phase 1b study with only 55 participants, so results may not apply to everyone. The drug may cause side effects or not improve anemia significantly.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

anemia anemia due to chronic disorder chronic kidney disease chronic renal failure syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANEMIA OF CHRONIC KIDNEY DISEASE CHRONIC KIDNEY DISEASES

Contacts and locations

Locations

Accel Research

DeLand, Florida, 32720, United States
CARE Institute - Boise Kidney

Boise, Idaho, 83706, United States
Center for Advanced Kidney Research PLC

Saint Clair Shores, Michigan, 48081, United States
Centricity Research

Columbus, Ohio, 43213, United States
Clinical Advancement Center, PLLC

San Antonio, Texas, 78212, United States
Endeavor Clinical Trials

San Antonio, Texas, 78240, United States
Flourish Research

Winter Park, Florida, 32789, United States
Mayo Clinic

Rochester, Minnesota, 55905, United States
Nephrology and Hypertension Specialists, PC-Dalton

Dalton, Georgia, 30720, United States
Total Research Group

Miami, Florida, 33126, United States
UCLA Clinical and Translational Research

Los Angeles, California, 90095, United States
US Renal Care Inc.

Lone Tree, Colorado, 80124, United States
Washington Nephrology Associates, LLP

Alexandria, Virginia, 22304, United States

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