TYPE 2 DIABETES

This study is testing whether using an over-the-counter continuous glucose monitor periodically—every 30 or 90 days—can help adults with type 2 diabetes who don't use insulin better manage their blood sugar. Researchers will compare these monitoring schedules to see if less frequ…

This study is testing a virtual support program for adults who have both type 2 diabetes and mental health challenges like anxiety or depression. It compares a new program of weekly health coaching calls and online tools with standard medical care. The goal is to see if this extr…

This early-stage study is testing whether montelukast, a medication commonly used for asthma and allergies, can help protect the kidneys and blood vessels in teenagers and young adults with type 2 diabetes. Researchers believe diabetes causes inflammation that damages these organ…

This study tests if adding couples counseling to a walking program helps people with type 2 diabetes become more active and improve their blood sugar control. 200 couples, where one person has type 2 diabetes, will get step counters and walking goals. Half the couples will also g…

This study aims to clear up confusion about whether eating fruit is good or bad for people with type 2 diabetes. Researchers will feed 25 adults with type 2 diabetes (who are not on insulin) a diet high in whole fruit for 17 weeks. They will closely monitor changes in blood sugar…

This study is testing a personalized diet program to help Chinese and Vietnamese Americans manage their type 2 diabetes. For 24 weeks, 120 participants will use a continuous glucose monitor and may receive a culturally tailored diet plan if their blood sugar isn't improving. The …

This study aims to find out if using a continuous glucose monitor (a small sensor) is better than finger-prick tests at helping people with type 2 diabetes achieve remission. About 176 participants will follow a low-calorie meal replacement plan and education program. Half will u…

This study is testing a new support program for South Asians in New York City who have type 2 diabetes and are at risk for depression. The program uses trained community health workers to provide culturally sensitive help with managing diabetes and emotional well-being. Researche…

This study aims to see if a newer combination injection (iGlarLixi) works better and is safer than standard insulin treatments for adults in China whose type 2 diabetes is not well controlled on pills alone. About 1,300 participants will be randomly assigned to receive either the…

This study is testing a program called PROMOTE, which combines peer support from trained community health workers with remote monitoring of blood sugar levels. It aims to help 200 Black adults in Alabama who have uncontrolled type 2 diabetes better manage their condition. The goa…

This study is testing whether a series of short, interactive educational videos can help adults with type 2 diabetes manage their condition better. Sixty participants will be randomly assigned to either receive the video program or continue with their standard care. The goal is t…

This study is testing whether a natural dietary fiber called oligofructose, found in foods like onions and bananas, can help people with type 2 diabetes better manage their condition. For 12 weeks, 100 Saudi adults (50 with diabetes and 50 without) will take either the fiber supp…

This study is testing whether a new computer tool in doctors' electronic health records can help improve blood sugar management for people with type 2 diabetes who use insulin. The tool combines data from continuous glucose monitors with treatment guidelines to give doctors clear…

This study will compare a new diabetes medication called cofrogliptin (taken once every two weeks) with an existing medication called acarbose (taken three times daily) in 200 people with type 2 diabetes who haven't tried medication before. Researchers want to see which drug work…

This study is testing if an automated insulin delivery system can help people with type 2 diabetes who are on kidney dialysis. The system uses a continuous glucose monitor and an insulin pump to automatically adjust insulin, aiming to keep blood sugar in a safe range. Researchers…

This study aims to compare the effectiveness and safety of two diabetes medications, cofrogliptin and linagliptin, when added to insulin therapy. It will follow nearly 600 Chinese adults with type 2 diabetes whose blood sugar isn't well controlled on their current treatment. The …

This study aims to see if taking a 20-minute walk after each meal helps pregnant women with Type 2 diabetes manage their blood sugar levels better. Researchers will compare two groups of about 40 participants: one group that walks after meals and one that does not. The goal is to…

This study aims to find the best long-term treatment for people with type 2 diabetes whose blood sugar isn't well controlled on pills alone, even after they receive a short, intensive course of insulin therapy. Researchers will compare three different medication combinations to s…

This study offers a medical device treatment to people with type 2 diabetes who were in the placebo group of a previous trial. It aims to collect real-world safety and performance data on the Endogenex System, which is designed to help control blood sugar. The study will enroll a…

This study is testing an investigational injection called HS-20094 for adults with type 2 diabetes whose blood sugar is not well controlled by diet and exercise alone. Over 200 participants will be randomly assigned to receive either the real injection or a placebo (dummy shot) f…

This study aims to see if adding specific local Ugandan fruits and vegetables to meals can help people with type 2 diabetes better manage their blood sugar and cholesterol levels. Eight participants will eat five different test meals over five weeks, and researchers will closely …

This study aims to find out which of two telehealth approaches works better to help adults with physical disabilities manage type 2 diabetes and other chronic health conditions. It will compare digital health coaching (personal guidance) with remote patient monitoring (tracking h…

This study compares two common diabetes medications, dapagliflozin and empagliflozin, to see which works better for Indian patients with type 2 diabetes and higher body weight. Researchers will measure blood sugar control, weight changes, organ function, and treatment costs over …

This study aims to find out which type of continuous glucose monitor works better for people with type 2 diabetes who use insulin. Researchers will compare a real-time monitor that sends automatic alerts to a smartphone with a monitor that requires scanning to see glucose reading…

This study is testing whether a structured diet and lifestyle program can put type 2 diabetes into remission, meaning blood sugar returns to normal without medication. Researchers will compare this intensive program to standard medical care in 92 Malaysian adults with recent diab…

This study is for people with type 2 diabetes who are at high risk of breaking a bone due to osteoporosis. Researchers want to see if a drug called denosumab, when given with calcium and vitamin D, can make bones stronger and reduce the chance of new fractures. The goal is to fin…

This study is testing a new program where specially trained community pharmacists can prescribe medications to help slow kidney damage in people with type 2 diabetes. It focuses on adults who do not have a regular family doctor. Researchers will compare health outcomes for 120 pe…

This study compares a new weekly injection called HS-20094 against an established diabetes medication (dulaglutide) in people with type 2 diabetes. About 546 participants whose blood sugar isn't well controlled on metformin, with or without another common pill, will receive one o…

This study aims to see if using a continuous ketone monitor along with a special education plan can help lower the risk of diabetic ketoacidosis (DKA), a serious and dangerous condition, in adults with type 1 diabetes who are also taking SGLT2 inhibitor medications. It will compa…

This study is testing a new drug called HM11260C for adults with type 2 diabetes whose blood sugar is still too high despite taking two common medications (metformin and dapagliflozin). About 118 participants will be randomly assigned to receive either the new drug or a placebo (…

This study aims to see if a new drug called HDM1005 works as well or better than an existing drug called mazdutide for controlling blood sugar in adults with type 2 diabetes. It will involve about 912 people whose diabetes is not well-managed with their current metformin-based tr…

This study tests whether remote mindfulness education can help rural Black adults better manage type 2 diabetes and reduce the emotional distress that often comes with the disease. Researchers will compare an 8-week mindfulness program delivered via Zoom to standard diabetes educ…

This study aims to understand how fasting during the holy month of Ramadan affects people with type 2 diabetes. Researchers will compare 70 adults who choose to fast with those who do not, looking at their blood sugar control, how well they stick to their treatment plan, and thei…

This study aims to understand how type 2 diabetes affects blood platelets and whether these changes relate to inflammation and blood sugar levels. Researchers will compare blood test results from 100 diabetes patients and 100 healthy people during a single clinic visit. The study…

This study aims to understand how thinking skills, like memory and attention, affect physical abilities and quality of life in people with type 2 diabetes. Researchers will compare 80 people—half with diabetes and half without—by measuring their balance, walking ability, fear of …

This study aims to understand how well the medication semaglutide works in everyday life for people with type 2 diabetes or obesity. Researchers will look back at the health records of 400 Canadian patients to compare semaglutide's effects on blood sugar, weight, and heart and ki…

This study looks back at medical records to compare how well Ozempic protects against heart and kidney problems compared to other diabetes medications. Researchers will analyze data from 100,000 Chinese patients with type 2 diabetes who have taken these medications. The goal is t…

This study aims to find out if a special brain scan taken before surgery can predict which older patients with type 2 diabetes are most likely to experience confusion and delirium after an operation. Researchers will enroll 154 patients scheduled for liver tumor surgery and measu…

This study aims to find the best ways to help teens and young adults with type 2 diabetes get support for basic needs like food, housing, and transportation. Researchers will test different approaches, including text message reminders and connections to community health workers, …

This study aims to develop and test an artificial intelligence (AI) model, called a 'digital twin,' to predict how type 2 diabetes will progress in young people. Researchers will create these digital twins for 50 participants aged 10-21 and use them to simulate future blood sugar…

This study aims to understand if certain diabetes and weight-loss medications (like Ozempic and Mounjaro) cause harmful loss of muscle mass or weaken bones. Researchers will use advanced body scans and strength tests to track 20 patients starting these drugs over one year. The go…

This study aims to understand how having type 2 diabetes affects the quality of life of cancer patients receiving immunotherapy. Researchers will follow 920 patients for six months, comparing survey responses from those with and without diabetes. The goal is to see if diabetes ad…

This study aims to understand the connection between vitamin D levels and insulin resistance in people with type 2 diabetes. Researchers will measure vitamin D and a specific marker of insulin resistance in 165 participants. The goal is to gather knowledge about this relationship…

This study aims to better understand why blood sugar is high in type 2 diabetes by measuring how the liver makes new sugar from fat and other molecules. Researchers will compare this process in healthy, obese, and diabetic adults using special tracer infusions and blood tests. Th…

This registry aims to collect long-term safety and health outcome information from people with type 2 diabetes who have already been treated with the Endogenex System. It will follow up to 500 participants for five years to monitor their health after the procedure. The goal is to…

This study aims to understand how the medication semaglutide affects muscle health in people using it for type 2 diabetes or weight loss. Researchers will use detailed MRI scans and fitness tests to track changes in muscle and fat in the body and heart over one year. The goal is …

This study aims to understand how blood sugar is regulated by comparing two different testing methods. About 225 adults at risk for diabetes will wear a continuous glucose monitor at home for 10-14 days and also complete a standard hospital glucose test. Researchers will analyze …

This study aims to create a standard list of what to measure in future research on treatments that could slow or stop type 2 diabetes progression. It will gather opinions from 300 people, including diabetes researchers, healthcare professionals, and people living with the conditi…