Can starting multiple kidney drugs at once slow Diabetes-Related kidney damage?
NCT ID NCT07547878
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This pilot study tests whether starting four approved kidney disease medicines quickly (over about 8 weeks) is safe and effective for people with type 2 diabetes and chronic kidney disease. Researchers will compare this rapid approach to usual care, where medicines are started one at a time. The study involves 64 participants and will track kidney function, protein in urine, and how many people can stay on all four medicines for 6 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Finerenone, Semaglutide, and ACE inhibitors (Benazepril, Captopril, Enalapril, Fosinopril, Lisinopril, Moexipril, Perindopril, Quinapril, Ramipril, Trandolapril)
- What this could lead to
- If this approach works, it could show that starting multiple kidney-protecting medicines at once is safe and helps slow kidney damage in people with diabetes.
- What could go wrong
- This is a small pilot study with only 64 people, so results may not apply to everyone. Starting several medicines quickly could increase side effects like high potassium or low blood pressure.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for CHRONIC KIDNEY DISEASE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Baylor Scott and White Medical Center- Temple
Temple, Texas, 76508, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Daily pill could offer new hope for weight loss in east asian adults
- Aging kidneys under the microscope: could a simple test predict failure?
- Can a new graft keep dialysis access working longer?
- Can a common gout pill shield hearts in kidney disease?
- Blood test could predict who faces rapid kidney decline in diabetes
- Blood test may predict kidney decline in diabetes — a large trial investigates