Reversing diabetes may also reverse aging — a trial puts it to the test

NCT ID NCT07736040

Not yet recruiting Disease control Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University Source: ClinicalTrials.gov ↗

First seen Jul 30, 2026 · Last updated Jul 31, 2026 · Updated 1 time

Summary

This study tests whether putting type 2 diabetes into remission through a 24-week lifestyle program can also slow biological aging. Researchers will measure changes in an epigenetic clock called DunedinPACE, which tracks how fast the body is aging. The trial enrolls 100 Chinese adults aged 35 to 70 with type 2 diabetes and compares aging markers between those who achieve remission and those who do not.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: a 24-week comprehensive lifestyle intervention including a calorie-restricted low-carbohydrate diet and exercise program
What this could lead to: If successful, this could show that reversing type 2 diabetes may also slow biological aging, pointing toward a dual benefit of lifestyle changes.
What could go wrong: This is a small, early-stage study with only 100 participants, so results may not apply broadly. The lifestyle program is intensive and may be hard for many people to maintain long-term.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TYPE 2 DIABETES

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