Could a zap to the ear boost memory in diabetes patients?

NCT ID NCT07642518

Not yet recruiting Disease control Sponsor: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a mild electrical stimulation applied to the ear (via a small device) can improve memory and thinking in people with type 2 diabetes who also have mild cognitive impairment. The trial will involve 38 participants who will either receive the active stimulation or a sham (fake) version for 24 weeks. The main goal is to see if this non-invasive treatment can help slow or improve cognitive decline.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: transcutaneous auricular vagus nerve stimulation device
What this could lead to: If it works, this could point toward a non-drug, at-home treatment to slow memory decline in people with type 2 diabetes.
What could go wrong: This is a very small, early-stage trial with only 38 people, so results may not apply widely. The sham control group also receives a device, so the real benefit may be small or hard to detect.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MILD COGNITIVE IMPAIRMENT TYPE 2 DIABETES

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Other studies related to the condition(s) this trial covers.