The Affiliated Nanjing Drum Tower Hospital Of Nanjing University Medical School

This large study is testing if a short course of the anti-inflammatory drug colchicine, taken around the time of heart surgery, can reduce damage to organs like the heart and lungs. It will involve 768 patients undergoing planned heart surgery with a heart-lung machine. Researche…

This early-stage study is testing whether a woman's own stem cells, taken from her body fat, can help rebuild a healthy uterine lining to improve chances of pregnancy. It is for women who have not gotten pregnant due to a persistently thin or scarred uterus that hasn't responded …

This study is testing a new, personalized vaccine designed to teach the immune system to attack leftover cancer cells after surgery. It is for people with colorectal or pancreatic cancer who have a specific genetic change (KRAS mutation) and a high risk of the cancer returning. T…

This study is testing if a weekly injection called mazdutide can slow down or improve memory and thinking problems in people who have both type 2 diabetes and early dementia. Over 76 weeks, 420 participants will receive either the active drug or a placebo (dummy injection) to see…

This is an early-stage study exploring a new treatment for women who have trouble getting pregnant or have had miscarriages, which may be linked to overactive immune cells in the uterus. Doctors take a small amount of a patient's blood, grow and modify her own immune cells in a l…

This study is observing how well a diabetes medication called Proline Plus Empagliflozin works in real-world settings for people with type 2 diabetes. Researchers will follow 3,000 patients for up to 48 weeks to see how effectively it controls blood sugar and monitor for any side…

This study is testing whether a new, less invasive surgery using AI-guided robots can help people recover better from a severe type of stroke caused by a large brain bleed. It will compare the robotic procedure to traditional brain surgery methods. The main goal is to see if pati…

This study is testing whether adding a drug called tislelizumab to standard treatments works better for advanced head and neck tumors. It will involve 29 adults with specific types of these cancers who haven't had prior treatment. Researchers will see if the combination helps shr…

This study is testing a new combination of drugs for people with advanced pancreatic cancer that has spread and has gotten worse after their first round of chemotherapy. The treatment mixes several types of drugs—chemotherapy, immunotherapy, and a drug that blocks tumor blood sup…

This study is testing if adding the anti-inflammatory drug ketorolac to standard emergency care helps patients recover better from a life-threatening tear in their main heart artery (Type A aortic dissection). 360 patients scheduled for emergency surgery will receive either ketor…

This early-stage study is testing a new type of treatment called universal anti-CD70 CAR-T (CHT101) for people with severe lupus that hasn't responded to standard medications. It aims to see if this advanced cell therapy is safe and can effectively control the disease. The study …

This study is testing a medication called efsubaglutide alfa to see if it can help people who are still obese six months after having metabolic (weight loss) surgery. It will involve 60 participants who will receive either the real drug or a placebo (dummy treatment) to compare r…

This study compares two pain medications (acetaminophen and hydromorphone) for treating sudden chest pain in emergency situations. Researchers will observe 30 adult patients to see which medication provides better pain relief with fewer side effects. The goal is to help doctors c…

This study aims to understand how the brains and metabolisms of people with obesity react differently to sugars, fats, and proteins compared to people of a healthy weight. Researchers will give 60 participants different liquid meals and use brain scans and blood tests to measure …

This study follows 300 patients with severe, end-stage heart failure who receive a mechanical heart pump (LVAD) as part of their standard care. Researchers will track their health, survival, and complications for 3-5 years to understand long-term outcomes. They will also analyze …