The Affiliated Nanjing Drum Tower Hospital Of Nanjing University Medical School

This study compares two ways to remove small rectal neuroendocrine tumors (less than 1 cm). The new method, called modified double snare EMR, may be as effective as the standard ESD procedure but faster and with fewer complications. About 118 adults with these tumors will be rand…

This study compares starting dialysis early versus waiting for kidney damage in people who have swallowed a large amount of diquat herbicide. About 267 adults with severe poisoning will be randomly assigned to one of two approaches. The goal is to see if early dialysis reduces de…

This study tests a personalized approach for people with advanced liver cancer that cannot be removed by surgery. Researchers will analyze the tumor's metabolism (how it uses fat for energy) to assign each patient to a specific treatment combination. The goal is to see if this ta…

This study compares two minimally invasive treatments for a type of brain aneurysm (a bulging blood vessel) in the middle cerebral artery. About 140 adults will receive either a flow diverter or a stent-assisted coiling procedure. The goal is to see which method more completely s…

This study tests whether a new cell therapy can help people who have trouble getting or staying pregnant due to abnormal uterine natural killer (NK) cells. The treatment uses a person's own blood cells, turned into special decidual-like NK cells in a lab, and then placed into the…

This study tests a combination of two drugs (carilizumab and apatinib mesylate) plus radiation therapy as a first treatment for advanced mucosal melanoma, a rare and aggressive skin cancer. About 30 adults who have not had prior systemic treatment will receive this triple therapy…

This early study tests a virus-based treatment (phage therapy) in 6 adults aged 18–65 with drug-resistant urinary tract infections. Participants receive the phage cocktail for 2–3 days and are followed for up to 4 weeks. The goal is to see if it safely clears the infection and im…

This study tests whether starting a type of dialysis (CVVHDF) immediately after blood filtering (hemoperfusion) can improve survival in people with severe diquat poisoning. Diquat is a herbicide that can cause rapid organ failure. The trial will enroll 24 adults who have high lev…

This study tests a drug called entinostat combined with standard chemotherapy for people with advanced bladder cancer that has gotten worse after initial treatment. The goal is to see if this combination can shrink tumors or slow the disease. About 29 adults with measurable tumor…

This early study tests a new treatment called CHT105 for people with lupus nephritis that hasn't responded to standard therapies. CHT105 uses specially engineered immune cells from healthy donors to target and destroy the faulty immune cells driving the disease. The main goals ar…

This study checks if a new portable mass spectrometry kit can accurately measure diquat (a toxic herbicide) in human blood samples. Researchers will compare results from 60 patients with suspected poisoning against the standard lab method. The goal is to see if the portable devic…

This study tests whether taking fish oil by mouth can prevent or lessen peripheral neuropathy—a common, painful nerve damage side effect—in people receiving the chemotherapy drug bortezomib for multiple myeloma. Researchers will enroll 200 adults who have not yet started bortezom…

This study will use artificial intelligence to create a tool that predicts a person's risk of head and neck cancer. Researchers will analyze data from 3000 adults, including their medical history, lifestyle, and voice symptoms. The goal is to help doctors catch these cancers earl…