Ear-Zap device aims to boost weight loss in stubborn obesity
NCT ID NCT07630597
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study tests a device that gently stimulates a nerve in the ear (taVNS) to help overweight or obese people who didn't lose much weight after 12 weeks of diet and exercise. 24 participants will get either real or sham stimulation twice daily for 12 more weeks, while continuing lifestyle changes. The goal is to see if the device leads to greater weight loss and improvements in body composition and metabolism.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
transcutaneous auricular vagus nerve stimulation (taVNS) device
What this could lead to
If it works, this could offer a new, non-invasive option to help people with obesity who struggle to lose weight through lifestyle changes alone.
What could go wrong
This is a very small, early pilot study with only 24 participants. The effect may be small or no better than sham stimulation, and results may not apply to everyone.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Department of Endocrinology, the Affiliated Drum Tower Hospital of Nanjing University Medical School
RECRUITINGNanjing, Jiangsu, 210008, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••