Ear-Zap device aims to boost weight loss in stubborn obesity
NCT ID NCT07630597
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study tests a device that gently stimulates a nerve in the ear (taVNS) to help overweight or obese people who didn't lose much weight after 12 weeks of diet and exercise. 24 participants will get either real or sham stimulation twice daily for 12 more weeks, while continuing lifestyle changes. The goal is to see if the device leads to greater weight loss and improvements in body composition and metabolism.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- transcutaneous auricular vagus nerve stimulation (taVNS) device
- What this could lead to
- If it works, this could offer a new, non-invasive option to help people with obesity who struggle to lose weight through lifestyle changes alone.
- What could go wrong
- This is a very small, early pilot study with only 24 participants. The effect may be small or no better than sham stimulation, and results may not apply to everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Department of Endocrinology, the Affiliated Drum Tower Hospital of Nanjing University Medical School
RECRUITINGNanjing, Jiangsu, 210008, China
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