Can a common gout pill protect the heart and lungs during surgery?

NCT ID NCT06118034

Recruiting now Disease control Sponsor: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether the anti-inflammatory drug colchicine can reduce organ damage after heart surgery. About 768 adults aged 50-80 having planned heart surgery will take either colchicine or a placebo before and after their operation. Researchers will track complications like atrial fibrillation, heart attack, and lung injury.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: colchicine
What this could lead to: If it works, this could reduce serious complications like atrial fibrillation, heart attack, and lung injury after heart surgery.
What could go wrong: This is a phase 3 trial, but colchicine may cause gastrointestinal side effects and may not reduce complications as hoped. Results may not apply to all heart surgery patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

heart disorder inflammatory disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARDIAC DISEASE INFLAMMATORY RESPONSE

Contacts and locations

Locations

Dong-Jin Wang
RECRUITING

Nanjing, Jiangsu, 210008, China

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