CARDIAC DISEASE

This large study is testing if a short course of the anti-inflammatory drug colchicine, taken around the time of heart surgery, can reduce damage to organs like the heart and lungs. It will involve 768 patients undergoing planned heart surgery with a heart-lung machine. Researche…

This study is testing the safety and performance of two specific heart pacing leads when placed in a particular area of the heart's electrical system. Researchers will follow 200 adult patients for 6 months after implant to check for complications like infection, lead movement, o…

This study is testing if giving the blood thinner heparin during a common heart test prevents a complication where the wrist artery used for access gets blocked. About 1,623 patients having a planned heart catheterization through the wrist will be randomly assigned to receive no …

This large Phase 3 trial is testing whether adding two common medications to standard care can prevent future strokes, heart attacks, and other major vascular problems in high-risk patients who have recently had a stroke. It will compare a low-dose anti-inflammatory drug (colchic…

This study compares two different blood vessel grafts used during heart bypass surgery in women. Researchers want to see whether using a vein from the leg (with a special 'no-touch' technique) or an artery from the arm works better for keeping blood flowing to the heart long-term…

This study is testing whether new artificial intelligence (AI) software can improve heart MRI scans. Researchers will compare AI-enhanced scans to standard scans in 50 adults who need a heart MRI. They will measure scan time, image quality, and how satisfied patients are with the…

This study is testing if a specific nerve block, given after heart surgery, can help control pain better. Researchers want to see if it reduces the need for strong opioid painkillers and lowers patients' pain scores. The study will involve 75 adults having planned heart surgery, …

This study aims to monitor the long-term safety and performance of Boston Scientific heart rhythm devices, like pacemakers and defibrillators, after they are approved for use. It will enroll up to 12,500 patients who receive these devices as part of their standard medical care. T…

This study aims to better understand how medicines work in critically ill children with heart conditions. Researchers will collect leftover blood samples from about 2000 children already receiving standard medications in the cardiac intensive care unit. The study only observes ex…

This study aims to collect information to help doctors better predict which older patients are at higher risk of complications after hip fracture surgery. It will compare two different assessment tools: a standard heart health check and a newer 'frailty score' designed for hip fr…