Blood thinner may keep wrist arteries open after heart procedure

NCT ID NCT04374799

Recruiting now Disease control Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether giving heparin (a blood thinner) during heart catheterization through the wrist can prevent the radial artery from becoming blocked afterward. About 1,600 patients will be randomly assigned to receive no anticoagulant, a low dose, or a high dose of heparin. The main goal is to see if heparin reduces artery blockage, while also checking for bleeding and other complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Heparin
What this could lead to: If it works, this could show that a simple blood thinner prevents artery blockages after a common heart procedure.
What could go wrong: This is a large trial, but heparin is already widely used; the benefit over placebo may be small. Bleeding risks are a concern.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

heart disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARDIAC DISEASE

Contacts and locations

Locations

Hamilton Health Sciences
RECRUITING

Hamilton, Ontario, Canada
London Health Sciences Centre
RECRUITING

London, Ontario, N6A5A5, Canada

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