CARDIAC DISEASE
Clinical trials for CARDIAC DISEASE explained in plain language.
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Blood filter during heart surgery may curb dangerous inflammation
Disease control CompletedThis study tested a device that filters the blood during complex heart surgery to remove inflammatory substances. Forty-one adults having high-risk heart procedures were enrolled. The goal was to see if the filter could reduce organ failure and improve recovery after surgery.
Matched conditions: CARDIAC DISEASE
Phase: NA • Sponsor: Centre Hospitalier Universitaire Vaudois • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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Heart surgery lung risk: which ventilation method wins?
Disease control CompletedThis study tested two ways of using a breathing machine during heart bypass surgery to see which one leads to fewer lung problems. Over 1,500 adults having planned heart surgery took part. One group had the breathing machine turned off during bypass, while the other received very…
Matched conditions: CARDIAC DISEASE
Phase: NA • Sponsor: CMC Ambroise Paré • Aim: Disease control
Last updated May 11, 2026 20:51 UTC
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New heart ultrasound dye passes early safety tests
Diagnosis CompletedThis study tested a new contrast agent called NH002 to see if it's safe for use in heart ultrasounds. 36 adults with heart disease received different doses of the agent. Researchers monitored vital signs, heart activity, and allergic reactions to determine safety.
Matched conditions: CARDIAC DISEASE
Phase: PHASE1, PHASE2 • Sponsor: Trust Bio-sonics, Inc. • Aim: Diagnosis
Last updated May 13, 2026 15:59 UTC
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Nurses with no ultrasound training can capture heart images using new software
Diagnosis CompletedThis study tested whether nurses with no prior ultrasound experience could use HeartFocus software to take heart ultrasound pictures good enough for doctors to analyze. 240 patients each had two heart ultrasounds: one by a nurse using the software and one by an expert. Cardiologi…
Matched conditions: CARDIAC DISEASE
Phase: NA • Sponsor: DESKi • Aim: Diagnosis
Last updated May 04, 2026 16:20 UTC
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Breathing trick eases pain and fear after heart surgery, study finds
Symptom relief CompletedThis study tested a breathing exercise called the active cycle breathing technique in 120 adults who had just had heart surgery. The exercise combines controlled breathing, deep breaths, and coughing to help clear the lungs and reduce pain. Researchers measured changes in breathi…
Matched conditions: CARDIAC DISEASE
Phase: NA • Sponsor: Damanhour University • Aim: Symptom relief
Last updated May 18, 2026 12:01 UTC
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New combo of nerve blocks eases pain after Open-Heart surgery
Symptom relief CompletedThis study looked at whether combining two types of nerve blocks (recto-intercostal and pecto-intercostal) can better control pain after open-heart surgery. Forty adults having heart surgery through a breastbone incision received these ultrasound-guided injections. The goal was t…
Matched conditions: CARDIAC DISEASE
Phase: NA • Sponsor: Medipol University • Aim: Symptom relief
Last updated May 15, 2026 11:53 UTC
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Brain oxygen watch during heart surgery may shield memory
Knowledge-focused CompletedThis study looked at whether continuously measuring oxygen levels in the brain during heart surgery can help prevent memory or thinking problems afterward. It included 326 older adults having planned coronary bypass surgery. Researchers compared standard care to care guided by a …
Matched conditions: CARDIAC DISEASE
Phase: NA • Sponsor: Instituto Nacional de Cardiologia de Laranjeiras • Aim: Knowledge-focused
Last updated May 18, 2026 12:12 UTC
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Massive study reveals how diabetes drugs stack up for heart safety
Knowledge-focused CompletedThis study looked at over 386,000 adults with type 2 diabetes to compare four common second-line medications (GLP-1RAs, SGLT2is, DPP-4is, and sulfonylureas) for their effects on heart health and other outcomes. Researchers used real-world insurance data to see which drugs best pr…
Matched conditions: CARDIAC DISEASE
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated May 18, 2026 12:09 UTC
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New app and booklet aim to boost heart surgery recovery
Knowledge-focused CompletedThis study tested a new discharge education program for people recovering from open heart surgery. The program included a booklet and a mobile app, and patients were followed for 12 weeks by phone. The goal was to see if the program helped improve recovery and quality of life. 70…
Matched conditions: CARDIAC DISEASE
Phase: NA • Sponsor: Istanbul University - Cerrahpasa • Aim: Knowledge-focused
Last updated May 18, 2026 11:59 UTC
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Can a simple stepper test measure heart health?
Knowledge-focused CompletedThis study looked at whether a 6-minute stepper test is a good way to measure exercise ability in people with heart disease who are in cardiac rehab. About 60 adults with heart conditions did the stepper test and also a standard walking test. The goal was to see if the stepper te…
Matched conditions: CARDIAC DISEASE
Phase: NA • Sponsor: Lille Catholic University • Aim: Knowledge-focused
Last updated May 14, 2026 12:03 UTC
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Smart wristband tracks heart surgery recovery steps
Knowledge-focused CompletedThis study tested whether a simple electronic wristband could help track how much patients move after heart surgery. 137 adults wore the band for two months after leaving the hospital. The goal was to measure daily steps and find early signs of recovery or complications.
Matched conditions: CARDIAC DISEASE
Sponsor: CMC Ambroise Paré • Aim: Knowledge-focused
Last updated May 13, 2026 15:59 UTC
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Which risk score best predicts heart surgery survival?
Knowledge-focused CompletedThis study looked at 320 adults who had heart surgery to see how well two risk scores (EuroSCORE-II and POSPOM) predict death in the hospital. Researchers used past medical records and did not give any new treatments. The goal is to find out which score is more reliable for plann…
Matched conditions: CARDIAC DISEASE
Sponsor: Istanbul University - Cerrahpasa • Aim: Knowledge-focused
Last updated May 12, 2026 13:40 UTC