New blood filter may shield heart surgery patients from organ failure

NCT ID NCT07532174

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a device called Efferon LPS that filters harmful substances from the blood during and after heart surgery. The goal is to see if it can reduce the risk of multiple organ failure, a serious complication. Researchers will enroll 60 adults having heart surgery with a heart-lung machine. The device is used twice: once during surgery and once within 24 hours after.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Efferon LPS device (blood filter cartridge that removes toxins and inflammatory substances)

What this could lead to

If it works, this device could lower the chance of multiple organ failure after heart surgery, helping patients recover better.

What could go wrong

This is a small early study with only 60 patients, so results may not apply to everyone. The device adds extra steps to surgery and could have unknown side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

heart disorder multiple organ dysfunction syndrome prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Almazov National Medical Research Centre

    RECRUITING

    Saint Petersburg, Russia

    Contact Email: •••••@•••••

  • Pavlov First Saint Petersburg State Medical University

    RECRUITING

    Saint Petersburg, Russia

    Contact Email: •••••@•••••

  • Regional State Budgetary Healthcare Institution "Altai Regional Cardiological Dispensary"

    RECRUITING

    Barnaul, Russia

    Contact Email: •••••@•••••