New blood filter may shield heart surgery patients from organ failure

NCT ID NCT07532174

Recruiting now Disease control Sponsor: Efferon JSC Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a device called Efferon LPS that filters harmful substances from the blood during and after heart surgery. The goal is to see if it can reduce the risk of multiple organ failure, a serious complication. Researchers will enroll 60 adults having heart surgery with a heart-lung machine. The device is used twice: once during surgery and once within 24 hours after.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Efferon LPS device (blood filter cartridge that removes toxins and inflammatory substances)
What this could lead to: If it works, this device could lower the chance of multiple organ failure after heart surgery, helping patients recover better.
What could go wrong: This is a small early study with only 60 patients, so results may not apply to everyone. The device adds extra steps to surgery and could have unknown side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

heart disorder multiple organ dysfunction syndrome prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARDIAC DISEASE MULTIPLE ORGAN DYSFUNCTION SYNDROME

Contacts and locations

Locations

Almazov National Medical Research Centre
RECRUITING

Saint Petersburg, Russia
Pavlov First Saint Petersburg State Medical University
RECRUITING

Saint Petersburg, Russia
Regional State Budgetary Healthcare Institution "Altai Regional Cardiological Dispensary"
RECRUITING

Barnaul, Russia

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