Could a simple nerve block cut opioid use after heart surgery?

NCT ID NCT05833048

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether a rectus sheath block, a type of nerve block using local anesthetic, can reduce pain and the need for opioid painkillers after cardiac surgery. Researchers will compare opioid use and pain scores in 75 adults who receive the block versus those who do not. The goal is to improve pain control and potentially speed recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
rectus sheath block (a nerve block with local anesthetic)
What this could lead to
If it works, this could offer a better way to manage pain after heart surgery, reducing the need for strong painkillers.
What could go wrong
This is a small, early-stage trial with only 75 participants. The block may not significantly reduce pain or opioid use, and results may not apply to all heart surgery patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

heart disorder Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Mount Sinai Morningside Hospital Center

    RECRUITING

    New York, New York, 10023, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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