Could a simple nerve block cut opioid use after heart surgery?
NCT ID NCT05833048
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests whether a rectus sheath block, a type of nerve block using local anesthetic, can reduce pain and the need for opioid painkillers after cardiac surgery. Researchers will compare opioid use and pain scores in 75 adults who receive the block versus those who do not. The goal is to improve pain control and potentially speed recovery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- rectus sheath block (a nerve block with local anesthetic)
- What this could lead to
- If it works, this could offer a better way to manage pain after heart surgery, reducing the need for strong painkillers.
- What could go wrong
- This is a small, early-stage trial with only 75 participants. The block may not significantly reduce pain or opioid use, and results may not apply to all heart surgery patients.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Mount Sinai Morningside Hospital Center
RECRUITINGNew York, New York, 10023, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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