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Can a nerve block quiet the brain during gallbladder surgery?

NCT ID NCT07818954

Knowledge-focused Sponsor: Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 14, 2026 · Last updated Sep 15, 2026 · Updated 1 time

Summary

Researchers observe adults having laparoscopic gallbladder removal under general anesthesia. They compare patients who receive intravenous remifentanil alone with those who also receive an ultrasound-guided subcostal TAP nerve block, a procedure that numbs the abdominal wall. The study tracks how much pain medicine patients need, along with brain wave readings such as Bispectral Index values, alpha-band activity, and burst suppression. It also records postoperative pain, recovery quality, and hospital stay.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
an ultrasound-guided subcostal transversus abdominis plane block, a nerve block that numbs the abdominal wall
What this could lead to
If the nerve block reduces pain medicine needs and changes brain wave patterns during surgery, it could support its use in gallbladder operations and guide how anesthesiologists monitor sedation depth.
What could go wrong
This is a small observational study of 60 people, so it can show links but not prove cause and effect. Patients receive whatever pain relief their anesthesiologist chooses, which may blur the comparison between groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2026

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients aged 18 years or older with ASA physical status I-III who are scheduled to undergo laparoscopic cholecystectomy under general anesthesia at Sancaktepe Sehit Prof. Dr. Ilhan Varank Training and Research Hospital and who provide written informed consent will be included. Patients will be evaluated according to the perioperative analgesic technique selected by the attending anesthesiologist as part of routine clinical care.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18 years or older * American Society of Anesthesiologists (ASA) physical status I-III * Scheduled to undergo laparoscopic cholecystectomy under general anesthesia * Written informed consent provided by the participant or, when applicable, the legally authorized representative Exclusion Criteria: * Refusal to participate in the study * American Society of Anesthesiologists (ASA) physical status IV-V * Known allergy or hypersensitivity to medications used during perioperative anesthetic or analgesic management

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Intraoperative nociception Laparoscopic cholecystectomy Postoperative pain

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Sancaktepe Şehit Prof. Dr. İlhan Varank Training and Research Hospital

    RECRUITING

    Istanbul, Turkey (Türkiye)

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