INFLAMMATORY RESPONSE

This study is testing if adding a 12-week supervised exercise program to standard antidepressant medication helps people with depression feel better. Researchers want to see if exercise reduces brain inflammation and improves symptoms more than medication alone. They will enroll …

This large study is testing if a short course of the anti-inflammatory drug colchicine, taken around the time of heart surgery, can reduce damage to organs like the heart and lungs. It will involve 768 patients undergoing planned heart surgery with a heart-lung machine. Researche…

This study is testing if getting a flu shot right after a heart attack can help reduce harmful inflammation in the heart's arteries. Researchers will compare a real flu vaccine to a placebo (saltwater shot) in 90 recent heart attack patients. They will use special heart scans and…

This study is testing if giving the drug tranexamic acid (TXA) very early after a traumatic brain injury can help control the body's harmful inflammatory response. Researchers will compare TXA to a placebo in 60 adults with mild-to-moderate head injuries to see if it reduces infl…

This study aims to understand how two common treatments for lower back pain from a slipped disc affect inflammation in the body. Researchers will measure specific inflammation markers in the blood of 128 adults before and after they receive either physical therapy or a steroid in…

This study aims to understand how eating high-fat meals affects inflammation and pain sensitivity in people living with chronic spinal cord injury. Researchers will compare blood markers and pain tests after participants eat different meals. The goal is to learn how body composit…

This study aims to understand how natural hormone changes during the menstrual cycle affect women's exercise experience and recovery. Researchers will measure muscle soreness, inflammation, and perceived difficulty after challenging downhill running in 30 young women. The goal is…