INFLAMMATORY RESPONSE

This study tests whether colchicine, a common anti-inflammatory drug, can reduce organ damage after heart surgery. About 768 adults aged 50-80 having planned heart surgery will receive colchicine or a placebo. Researchers will measure heart, lung, and kidney injuries, as well as …

This study tests whether giving tranexamic acid early after a traumatic brain injury can lower harmful inflammation. Researchers will measure inflammation using a blood test called NLR. The trial enrolls 60 adults with mild to moderate head injuries, treated within 8 hours.

This study tests whether getting a flu vaccine (outside flu season) can lower inflammation in the arteries of people who recently had a heart attack. About 90 adults who had a specific type of heart attack and a stent procedure will be randomly assigned to receive either the flu …

This study looks at whether adding a structured exercise program to standard antidepressant treatment can improve symptoms of major depression. Researchers will also use brain scans and blood tests to understand how exercise might reduce inflammation and change brain activity. Ab…

This study looks at how different amounts of resistance (strength) training affect inflammation in adults aged 60-75. Participants will be placed into one of three training groups (low, medium, or high volume) or a non-exercise group for 4 weeks, followed by 4 weeks of rest. The …

This study looks at how body composition and diet affect pain and inflammation in people with chronic spinal cord injury. Researchers will measure pain sensitivity and blood markers of inflammation after participants eat a high-fat or moderate-fat meal. The goal is to understand …

This study looks at what happens to inflammation in the body when menthol cigarette smokers switch to non-menthol cigarettes. Researchers want to see if this change could lower the risk of heart disease. About 68 adults who smoke menthol cigarettes daily will be followed for seve…

This study looks at how natural changes in estrogen and progesterone throughout the menstrual cycle influence how ready women feel to exercise, how hard they perceive a workout, and how their bodies recover afterward. Researchers will measure perceived readiness, difficulty, musc…

This study looks at whether a Daoist practice called Zhanzhuang (standing like a tree) can improve overall well-being, reduce stress, and lower inflammation. Researchers will compare it to a sham wall squat in 120 young adults aged 18-25 over 12 months. The goal is to understand …

This study looks at 128 adults with back pain from a slipped disc. Researchers will measure inflammation-related substances in the blood before and after physical therapy or a steroid injection. The goal is to see if these markers can help predict which treatment works better and…