INFLAMMATORY RESPONSE

This study tested whether giving a single, strong dose of steroids to people right after a major heart attack (STEMI) could reduce the amount of heart muscle that gets permanently damaged. The steroid was given before the standard emergency procedure to open the blocked artery. T…

This study looked at whether a sedative called dexmedetomidine can protect the brain during surgery to remove a brain tumor. 56 adults having brain tumor surgery received either the drug or a placebo. The goal was to see if the drug reduces brain damage and inflammation, helping …

This study tested whether giving the steroid methylprednisolone before and during heart surgery could reduce dangerous inflammation in infants under one year old. Over 1,200 babies were randomly assigned to receive either the steroid or a placebo (salt water). Researchers tracked…

This study looked at whether the flu vaccine can reduce inflammation in people with stable coronary artery disease. Inflammation plays a key role in heart disease progression. The trial involved 47 adults aged 60 and older with stable heart disease, who received the flu vaccine e…

This study tested whether wearing special light glasses for 30 minutes each morning could help breast cancer patients feel less tired, sleep better, and think more clearly during treatment. The trial included 260 women with early-stage breast cancer, plus a healthy comparison gro…

This study tested whether giving a single high dose of corticosteroids before major surgery helps elderly patients (60+) recover faster. The goal was to reduce muscle weakness and improve overall recovery. 751 participants were randomly assigned to receive either the steroid or n…

This pilot study tested whether manual lymphatic drainage, a gentle massage technique, is safe and feasible for patients recovering from septic shock. Researchers enrolled 24 adults in the ICU and compared those who received the massage plus usual care to those who received usual…

This study tested whether a PENG block (a numbing injection near the hip) can lower inflammation and 30-day death risk in patients over 65 having hip fracture surgery. Researchers measured blood markers of inflammation and pain levels in 60 patients. The goal is to see if this ne…

This study looked at 128 adults with back pain from a herniated disc. Researchers measured certain inflammation-related substances in the blood before and after physical therapy or a steroid injection. The goal was to see if these substances change with treatment and if they rela…

This study looked at how eating egg whites, egg yolks, or whole eggs every day for four weeks changes HDL (good cholesterol) and immune cell profiles in younger (18-30) and older (50-75) adults. Participants followed a healthy diet and gave blood samples. The goal was to see if d…

This study looked at 264 people with chronic lower back and leg pain caused by a pinched nerve. Researchers wanted to see if routine blood test results could predict who would get good pain relief from a combination of two treatments: a nerve block and a short electrical pulse to…

This completed study looked at 72 newborns who had seizures shortly after birth. Researchers measured inflammation markers in their blood and tracked whether they later developed epilepsy. The goal was to understand if inflammation plays a role in epilepsy risk after neonatal sei…

This completed observational study at a single hospital in China enrolled 16 adults with sepsis in the ICU. Researchers measured specific memory CD8+ T cells in the blood at several time points to see if their numbers or activity relate to how severe the sepsis is or whether pati…