INFLAMMATORY RESPONSE

This study tested whether giving a single, strong dose of steroids (glucocorticoids) to people having a major heart attack, before they undergo emergency artery-opening treatment, can reduce the amount of permanent heart muscle damage. The trial involved 530 adults with a specifi…

This study tested whether giving the steroid methylprednisolone to infants before and during heart surgery could reduce dangerous inflammation and improve recovery. Over 1,200 infants under one year old were randomly assigned to receive either the steroid or a placebo. Researcher…

This study looked at whether the flu vaccine can reduce inflammation in 47 older adults with stable coronary artery disease. Researchers measured blood markers of inflammation before and after vaccination. The goal was to see if the vaccine might lower heart risks by calming the …

This study tested whether a sedative called dexmedetomidine can protect the brain during surgery to remove a brain tumor. 56 adults having brain tumor surgery received either the drug or a placebo. The researchers measured markers of brain injury and oxygen use to see if the drug…

This study tested whether giving a single high dose of corticosteroids before major surgery helps elderly patients (60+) recover faster by reducing inflammation and muscle weakness. 751 participants having heart, lung, colon, or prostate surgery were enrolled. The main focus was …

This small pilot study tested whether manual lymphatic drainage (a gentle massage technique) is safe and practical for patients recovering from septic shock. Researchers enrolled 24 adults in the ICU to see if the procedure could be done without interfering with standard care or …

This study followed 72 newborns who had seizures shortly after birth to understand how inflammation might be linked to developing epilepsy later. Researchers measured seizure activity and checked which babies went on to have epilepsy. The goal was to gather information, not to te…

This study examined 16 ICU patients with sepsis to see if specific memory immune cells (called Tcm and Tem) are linked to how severe the infection is and the risk of death. Researchers measured these cells in blood samples taken over 72 hours. The goal was to better understand th…

This study looked at 264 people with chronic back and leg pain to see if routine blood test results could predict who would benefit from a combined pain treatment (pulsed radiofrequency and steroid injection). Researchers analyzed markers of inflammation in the blood and compared…

This study looked at how eating egg whites, egg yolks, or whole eggs every day for four weeks changes good cholesterol (HDL) and immune cells in younger (18-30) and older (50-75) adults. 44 healthy men and women took part, following a healthy diet and giving blood samples. The go…

This study tested whether a PENG block (a type of nerve block) can reduce inflammation and improve survival in 60 older adults (over 65) having hip fracture surgery. Researchers measured blood markers of inflammation and tracked deaths within 30 days. The goal was to see if this …