Could inflammation after newborn seizures predict epilepsy?

NCT ID NCT04259125

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study looked at 72 newborns who had seizures shortly after birth. Researchers measured inflammation markers in their blood and tracked whether they later developed epilepsy. The goal was to understand if inflammation plays a role in epilepsy risk after neonatal seizures.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this research could help identify which newborns are at higher risk for epilepsy after seizures, leading to earlier monitoring or intervention.

What could go wrong

This is an observational study, not a treatment trial. It cannot prove cause and effect, and the small size (72 participants) limits how broadly the findings can be applied.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

epilepsy Inflammation inflammatory disease visual epilepsy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Boston Children's Hospital

    Boston, Massachusetts, 02115, United States

  • UCSF Benioff Children's Hospital Oakland

    Oakland, California, 94609, United States

  • University of California, San Francisco

    San Francisco, California, 94158, United States

  • University of Michigan, Mott Children's Hospital

    Ann Arbor, Michigan, 48103, United States