Ear injection aims to repair Diabetes-Linked hearing damage

NCT ID NCT07472907

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a single injection of CIL001 (Paliroden) into the ear to repair nerve damage that causes hearing problems in people with type 2 diabetes. The trial includes 135 adults aged 45-75 with diabetes for at least 5 years. Researchers will check safety and whether the injection improves the ability to hear speech in noisy settings.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
CIL001 (Paliroden)
What this could lead to
If it works, this could point toward a treatment for hearing loss caused by diabetes, and possibly help delay dementia.
What could go wrong
This is an early-phase trial with only 135 people, so results may not apply widely. The injection is new and safety is still being checked.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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