New combo aims to shield diabetic bones from breaking

NCT ID NCT07063797

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding denosumab to standard care can strengthen bones and prevent fractures in 358 adults with type 2 diabetes who are at high risk for breaks. Participants will receive the drug or a placebo, and researchers will measure changes in bone density and fracture rates over time. The goal is to find a better way to manage osteoporosis in diabetes.

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Conditions

The condition(s) this trial relates to.

bone fracture osteoporosis type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Huai'an First People's Hospital

    Huai'an, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Jiangxi Provincial People's Hospital

    Jiangxi, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kunshan Hospital of Traditional Chinese Medicine

    Kunshan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Peking Union Medical College Hospital

    Beijing, Dongcheng, 100730, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••