King of fruits takes on diabetes: Durian's effect on gut and glucose

NCT ID NCT07697612

Not yet recruiting Disease control Sponsor: Singapore General Hospital Source: ClinicalTrials.gov ↗

First seen Jul 13, 2026 · Last updated Jul 14, 2026 · Updated 1 time

Summary

This study explores whether eating durian daily for two weeks changes the gut microbiome, metabolism, and blood sugar levels in adults with type 2 diabetes. Forty participants will eat fresh durian pulp and undergo blood and stool tests, plus continuous glucose monitoring. The goal is to see if this tropical fruit can be part of diabetes management without harming glucose control.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: durian pulp
What this could lead to: If durian proves beneficial, it could offer a tasty dietary option for managing blood sugar and gut health in type 2 diabetes.
What could go wrong: This is a small, early-phase study without a comparison group, so results may not be conclusive. Durian is high in sugar and calories, which could worsen blood sugar control in some participants.

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Conditions

The condition(s) this trial relates to.

type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TYPE 2 DIABETES

Contacts and locations

Locations

Singapore General Hospital

Singapore, Singapore

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