Singapore General Hospital

This study tests a community-based care bundle for treating and preventing pressure injuries (bedsores) in older adults at home. 216 participants discharged from Singapore General Hospital will either receive the bundle (including special cushions, skin barriers, and caregiver tr…

This study tests whether emergency responders can safely use a special cooling vest on adults who have had a cardiac arrest and regained a pulse but remain unconscious. The vest is designed to cool the body quickly in the ambulance, which might protect the brain. The goal is to s…

This trial tests whether a new app and device can help community first responders give better CPR during out-of-hospital cardiac arrests. The enhanced system allows two-way audio and one-way video communication with dispatchers, plus real-time feedback on chest compressions. Rese…

This study tests whether a program of physical activity counseling and a personalized exercise plan can help stroke survivors become more active. Researchers will compare a group receiving this program plus usual care to a group receiving only usual care. The study involves 120 c…

This study compares two alignment techniques—kinematic and functional—used during robotic-assisted total knee replacement. 240 people with knee osteoarthritis will be randomly assigned to receive one of two types of implant inserts. Researchers will track how well patients forget…

This study tests whether a care coach-led team that combines palliative care and rehabilitation can improve quality of life for 770 adults with advanced cancer who are having major surgery. The program addresses physical, emotional, and functional needs before and after surgery. …

This study is testing whether AS01, an ingredient already used in some vaccines, can act like a personal trainer for your immune system. Researchers want to see if giving AS01 alone to healthy adults aged 21 to 59 can boost their overall ability to fight off infections. The study…

This study tracks 800 adults across Asia-Pacific who need minimally invasive colorectal surgery. Half will have the removed tissue taken out through a natural opening (anus or vagina), the other half through a small cut in the belly. Researchers will compare how many develop hern…

This study looks at how the relationship between doctors and patients affects the way medical decisions are made. Researchers will interview 300 patients and healthcare workers in Singapore to understand what makes a good partnership. The goal is to learn how these partnerships c…

This study compares a multilingual AI chatbot (PEAR) with standard face-to-face verbal consent for explaining anesthesia risks. About 120 adults having elective surgery will participate. The goal is to see if the chatbot improves patient understanding and reduces anxiety.

This study will check how often muscle loss (sarcopenia) happens in 300 adults with obesity. Researchers will measure muscle mass, strength, and physical function, and look at factors like age, diet, and activity. The goal is to help doctors better identify and manage this condit…

This study follows 2,200 adults with liver cirrhosis to find factors that predict severe complications like liver failure or death. Researchers will review existing medical records without requiring extra visits or tests. The goal is to help doctors identify high-risk patients so…

This study looks at how severe obesity and weight-loss surgery change natural chemicals in scalp hair. Researchers will track 60 adults—some with severe obesity scheduled for bariatric surgery and some healthy-weight controls—to see if hair chemistry can signal poor metabolic hea…

This study looks at whether a genetic test can help decide which men with prostate cancer can safely have a less invasive treatment called focal therapy, which targets only the tumor instead of the whole prostate. Researchers will enroll 130 men and use the test to classify their…