Could a simple vest cool the brain and save lives after cardiac arrest?

NCT ID NCT07421882

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether emergency responders can safely use a special cooling vest on adults who have had a cardiac arrest and regained a pulse but remain unconscious. The vest is designed to cool the body quickly in the ambulance, which might protect the brain. The goal is to see if this approach is practical and acceptable before planning a larger trial to check if it truly improves recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

CarbonCool® Cooling Vest

What this could lead to

If successful, this could pave the way for a larger trial that may show early cooling improves brain recovery after cardiac arrest.

What could go wrong

This is a small pilot study focused on feasibility, not effectiveness. The cooling vest may not improve outcomes, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cardiac arrest Death, Sudden, Cardiac Out-of-Hospital Cardiac Arrest sudden arrhythmia death syndrome sudden cardiac arrest

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National University Heart Centre, Singapore (NUHCS)

    RECRUITING

    Singapore, 119074, Singapore

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact