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Could a simple vest cool the brain and save lives after cardiac arrest?

NCT ID NCT07421882

Recruiting now Disease control Sponsor: Singapore General Hospital Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether emergency responders can safely use a special cooling vest on adults who have had a cardiac arrest and regained a pulse but remain unconscious. The vest is designed to cool the body quickly in the ambulance, which might protect the brain. The goal is to see if this approach is practical and acceptable before planning a larger trial to check if it truly improves recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
CarbonCool® Cooling Vest
What this could lead to
If successful, this could pave the way for a larger trial that may show early cooling improves brain recovery after cardiac arrest.
What could go wrong
This is a small pilot study focused on feasibility, not effectiveness. The cooling vest may not improve outcomes, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cardiac arrest Death, Sudden, Cardiac Out-of-Hospital Cardiac Arrest sudden arrhythmia death syndrome sudden cardiac arrest

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARDIOPULMONARY RESUSCITATION DEATH, SUDDEN, CARDIAC OUT-OF-HOSPITAL CARDIAC ARREST THERAPEUTIC HYPOTHERMIA

Contacts and locations

Locations

  • National University Heart Centre, Singapore (NUHCS)

    RECRUITING

    Singapore, 119074, Singapore

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