Gene test could spare prostate cancer patients from radical surgery

NCT ID NCT07282808

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether a genetic test can help decide which men with prostate cancer can safely have a less invasive treatment called focal therapy, which targets only the tumor instead of the whole prostate. Researchers will enroll 130 men and use the test to classify their cancer as low or high risk for coming back. Those with low-risk genetics will get focal therapy, while high-risk patients will be advised to have standard treatments like surgery or radiation. The goal is to see if this personalized approach keeps recurrence rates below 10%.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Decipher GC genetic test

What this could lead to

If successful, this could show that genetic profiling helps choose the right patients for focal therapy, leading to fewer side effects and better cancer control.

What could go wrong

This is an early observational study with only 130 participants. The genetic test may not accurately predict recurrence, and results may not apply to all prostate cancer patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

prostate adenocarcinoma prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Singapore General Hospital

    RECRUITING

    Singapore, Singapore

    Contact Phone: •••-•••-•••• Email: •••••@•••••