New biweekly diabetes pill could replace daily dosing

NCT ID NCT07198932

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study will compare two diabetes medications, cofrogliptin and linagliptin, when added to insulin therapy in Chinese adults with type 2 diabetes. About 594 participants will take either a biweekly or daily pill alongside their usual insulin. Researchers will track blood sugar control, side effects, and other health measures over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

cofrogliptin and linagliptin

What this could lead to

If successful, this could show that a biweekly pill (cofrogliptin) works as well as a daily pill (linagliptin) for controlling blood sugar in people with type 2 diabetes who already use insulin.

What could go wrong

This is a real-world observational study, not a controlled trial, so results may be less reliable. It is also limited to Chinese adults, so findings may not apply to other populations.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Insulin Resistance type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Affiliated Hospital of Hebei University

    Baoding, China

  • Beijing Luhe Hospital Affiliated to Capital Medical University

    Beijing, China

  • Qingpu Branch of Zhongshan Hospital Affiliated to Fudan University

    Shanghai, China

  • Shanghai Changzheng Hospital

    Shanghai, China

  • Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University

    Hangzhou, Zhejiang, China

  • Xi'an International Medical Center Hospital

    Xi'an, China

  • the First Medical Center of Chinese PLA General Hospital

    Beijing, China