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This trial tests two different contact lenses designed to slow down the progression of myopia (nearsightedness) in children aged 6 to 11. Each child wears one type of lens on each eye for six months, then switches, so researchers can compare how well each lens controls eye growth…

This completed study tested a special lens called HAL for people with nearsightedness (myopia). 88 participants wore either the HAL lens or a standard single vision lens. Researchers measured reading speed and how well they could see at different distances and contrasts. The goal…

This study tested two types of advanced glasses—lenslet spectacles and violet filter glasses—against standard single-vision lenses to see if they could slow the worsening of nearsightedness (myopia) in 90 people aged 8 to 20. Participants wore the glasses during all waking hours …

This study tested three low doses of atropine eye drops (0.01%, 0.03%, and 0.05%) in 95 children aged 6–18 with nearsightedness. The goal was to see which dose best slowed the worsening of myopia with the fewest side effects. Over 18 months, the 0.05% dose worked best at controll…

This study tested a drug called faricimab (VABYSMO®) against an existing treatment (ranibizumab) for people with vision loss caused by abnormal blood vessels growing in the back of the eye due to severe nearsightedness. The trial involved 280 participants who received either fari…

This study looked at whether adding bifocal glasses to daily atropine eye drops works better than atropine alone to slow down nearsightedness (myopia) in children. 210 kids aged 4-16 with worsening myopia took part. The main goal was to measure changes in their vision prescriptio…

This phase 3 study tested the long-term safety of LNZ101 eye drops, a combination of aceclidine and brimonidine, in 362 adults aged 45-75 with presbyopia (age-related blurry near vision). Participants used the drops regularly and were monitored for side effects. The study is comp…

This completed study tested whether bright light therapy, special glasses that create myopic defocus, low-dose atropine eye drops, or combinations of these can slow the progression of nearsightedness in schoolchildren. A total of 577 children aged 7-12 with myopia participated. T…

This study tested a new type of artificial lens (PODEYE TORIC) for people having cataract surgery who also have astigmatism, a condition where the eye is shaped like a football instead of a basketball. 261 adults received either the new lens or a standard lens to see if it safely…

This completed Phase 1 trial tested the VisuMax femtosecond laser to correct nearsightedness (myopia) in 357 adults aged 22 and older. The procedure removes a small lens-shaped piece of the cornea to reshape the eye and improve vision. Researchers measured how well the treatment …

This study looked at the long-term safety and performance of AcrySof PanOptix trifocal lenses in 211 people who had them implanted in both eyes 3 to 5 years earlier. Researchers checked vision and recorded any eye problems or device issues. The goal was to make sure these lenses …

This study tested a toric intraocular lens implant in 40 children aged 6 to 17 with cataracts and astigmatism (a condition where the eye is shaped like a football). The goal was to see if this special lens could improve vision better than standard surgery. All children had catara…

This study tested a special laser (femtosecond laser) to adjust an artificial lens already placed inside the eye after cataract surgery. The goal was to correct leftover blurriness or astigmatism so people need glasses less. Twelve adults with at least one diopter of remaining re…

This study tested the safety and effectiveness of the EVO/EVO+ Visian Implantable Collamer Lens (ICL) in 327 adults with moderate to high nearsightedness (with or without astigmatism). The lens is surgically placed inside the eye to correct vision. Researchers tracked side effect…

This completed trial tested whether a specially designed spectacle lens (CARE1.02) can slow the progression of myopia (nearsightedness) in teenagers aged 12 to 17. About 796 teens in Guangzhou, China, wore either the CARE1.02 lens or a standard single-vision lens for one year. Re…

This study tested three strengths of atropine eye drops (0.01%, 0.04%, and 0.1%) in 219 children with high myopia (severe nearsightedness). The goal was to see which dose best slows the worsening of vision and eye growth over two years. Children received one drop in each eye ever…

This study tested whether a new type of spectacle lens (partition multi-point defocus lens) is as good as another advanced lens (aspherical lenslets) at slowing the progression of nearsightedness (myopia) in children. 194 children aged 8 to 13 years wore the lenses for two years.…

This study looked at how well a special lens implant, called the Visian Toric ICL, works over two years for people with nearsightedness and astigmatism. A total of 125 participants received the implant, which sits behind the iris. The main goal was to see if the lens stays in pla…

This study tested special glasses called C.A.R.E. lenses in 100 children aged 6-12 with nearsightedness. The lenses have rings that change how light hits the eye to slow down eye growth. After 12 months, researchers measured changes in eye length and prescription strength to see …

This study looked at how often eye pressure rises after getting an EVO ICL lens implant to correct nearsightedness and astigmatism. Researchers measured pressure in 205 people right after surgery. The goal was to see how many eyes had high pressure, which can be a risk after this…

This study tested whether orthokeratology (OK) lenses, worn overnight, can slow the progression of nearsightedness (myopia) in children aged 8 to 15. The lenses reshape the cornea to change how light focuses on the retina. Researchers measured changes in eye length and retinal fo…

This study tested whether combining low-dose atropine eye drops with special soft contact lenses can slow the progression of high myopia (severe nearsightedness) in children aged 6-12. 120 children were split into three groups: one got the combo therapy, one got atropine alone wi…

This study tested whether a low-intensity red light device could slow the worsening of nearsightedness (myopia) in children aged 8 to 12. Forty children participated, with some using the red light treatment for 3 months while others did not. The main goal was to see if the treatm…

This study tested a special toric lens implant (RayOne EMV Toric) in 274 adults with cataracts and mild corneal astigmatism. Participants had cataract surgery and received either the toric lens or a standard monofocal lens. The goal was to see if the toric lens safely reduces blu…

This study tested two different types of contact lenses worn overnight to treat moderate nearsightedness (myopia) with or without astigmatism. Forty adults aged 18 and older with myopia between -4.00 and -6.00 diopters participated. The goal was to see which lens design better im…

This study tested ACUVUE Abiliti 1-Day soft contact lenses designed to manage nearsightedness (myopia) in children. Over 1 to 2 years, researchers measured changes in eye length and vision in 75 participants. The goal was to see if these daily-use lenses can safely slow the worse…

This study tested SYD-101 eye drops in 852 children with nearsightedness (myopia). The goal was to slow the worsening of vision over time. Children used the drops daily for up to 3 years. The study measured how much their eyesight changed, aiming to reduce the risk of serious eye…

This study tested whether special glasses (DIMS) are as good as overnight contact lenses (Ortho-K) at slowing myopia progression in children aged 6-12. Ninety kids wore either the glasses or the lenses for 18 months. The main goal was to see if the glasses were not worse than the…

This study tested a new virtual reality (VR) system designed to slow the worsening of nearsightedness (myopia) in children. 116 kids aged 6 to 12 with mild to moderate myopia used the VR training, which creates special visual signals to stop the eye from growing too long. The goa…

This study tested a new type of spectacle lens designed to slow the progression of myopia (nearsightedness) in children. 159 kids aged 6 to 12 wore either the test lens or a standard lens. Researchers measured changes in eye length and prescription strength over time to see if th…

This study followed 105 adults who received a special lens implant (Mini Toric Ready) during cataract surgery to also correct astigmatism. Researchers measured how well the lens improved vision and stayed in place at least one year after the procedure. The goal was to confirm the…

This study tested a new laser system called Cheetah to correct nearsightedness (myopia) with or without astigmatism. About 286 adults with mild to moderate nearsightedness received the treatment. The main goal was to see how many patients achieved clear vision without glasses one…

This completed study compared two common surgeries for moderate nearsightedness: FemtoLasik and implantable collamer lens (ICL) implantation. Researchers looked at how stable the vision correction was, contrast sensitivity, and higher-order aberrations in 60 adults aged 21-40. Th…

This study tested two types of daily disposable contact lenses—Buttermere and MiSight 1 Day—in 10 children and teenagers with myopia (nearsightedness). Each participant wore one lens type for a week, then switched to the other for a week. Researchers measured how clearly they cou…

This study tested whether Deseyne daily disposable contact lenses work as well as 1-Day Acuvue Moist lenses for people with nearsightedness. 81 adults wore both types of lenses and had their vision and eye health checked. The goal was to see if Deseyne is a safe and effective alt…

This study tested a new silicone hydrogel contact lens (MSiHy) for correcting nearsightedness. 134 adults who already wore contacts were randomly assigned to try either the new lens or a standard monthly lens. The goal was to see if the new lens provides clear vision and is safe …

This study tested toric intraocular lenses (IOLs) in 236 children aged 3 to 8 who had cataracts and at least 2.0 diopters of astigmatism. All children had cataract surgery and received the special lens implant. Researchers tracked their vision and eye health for three years to se…

This completed study tested how well delefilcon A contact lenses with different diameters and base curves fit the eyes of 257 people with nearsightedness. Researchers checked lens movement and centration right after insertion and again after 6 hours. The goal was to find which le…

This study tested two new devices that automatically measure vision in children aged 6 to 16. The devices use special lenses that adjust themselves, avoiding the need for eye drops that dilate the pupils. Researchers compared the results from 43 children to the standard dilation …

This study tested a new prototype device that uses light field technology to measure vision problems like nearsightedness and farsightedness. Researchers compared its accuracy to standard methods in 120 healthy adults. The goal was to see if this new approach could reliably deter…

This completed early-phase study tested a daily drink called Baby Drink, which contains lutein, blueberry extract, vitamins, and minerals, in 20 adults with mild myopia (nearsightedness less than 700 degrees). Participants took one 20 ml pack per day for one month. Researchers tr…

This study tested whether glasses made with a new prescription method (Essilor AVA) give better vision and comfort than standard glasses. About 120 adults with common vision problems wore both types of lenses for two weeks each. The goal was to see which people preferred and if t…

This completed pilot study tested two different daily disposable multifocal contact lenses in 74 adults aged 40 to 70 with presbyopia. Participants wore each lens type for about a week, and researchers measured how well they could see at distance, intermediate, and near distances…

This study tested how well people with astigmatism who had never worn contact lenses liked a new type of soft lens that is replaced every week. Forty adults wore the lenses for about three weeks and reported on their vision and comfort. The goal was to see if these lenses could b…

This study tested two types of daily disposable contact lenses for people with astigmatism to see which one felt more comfortable. 134 adults wore each lens for one week and rated their comfort. The goal was to find out which lens provided longer-lasting comfort and a better over…

This study tested a new type of daily disposable contact lens for people with astigmatism. 281 contact lens wearers tried the lenses to see how well they corrected vision, stayed in place, and felt comfortable. The goal was to make sure the new lenses are safe and work well for e…

This study tested a newer trifocal lens implant (Clareon PanOptix Pro) against an older one (Clareon PanOptix) in 71 adults having cataract surgery in both eyes. Each person got one of each lens, so their eyes could be compared directly. The goal was to see if the newer lens prov…

This study checked the safety and effectiveness of the CorVision microlens, a tiny implant placed in the cornea to help with presbyopia (age-related difficulty seeing up close). About 95 people who had the implant in an earlier study came back for a single 4-year follow-up visit.…

This study tested an eye drop called LNZ101 to help people with presbyopia (age-related trouble seeing up close) read without glasses. 469 adults aged 45-75 received the drops, and researchers measured how many gained clear near vision without losing distance vision on the first …

This study compared two types of lasers used to create the flap in LASIK eye surgery for nearsightedness. 120 adults each had one eye treated with the Intralase laser and the other with the Visumax laser. The goal was to see which laser caused less discomfort during surgery and l…

This study looked at how well contact lenses perform and how comfortable people find them. It included 36 adults who already wear soft contact lenses and have nearsightedness or farsightedness. Participants wore the lenses and had their vision tested after 10 hours.

This study compared two types of soft multifocal contact lenses (Proclear 1 Day and Clariti 1 Day) to see which one people liked better. 67 adults who already wore contact lenses and needed reading glasses tried both lenses and rated their overall satisfaction. The goal was to he…

This study compared two types of soft contact lenses to see which one people liked better for vision and comfort. 52 adults who wear contacts took part. They rated the lenses on a scale from 0 to 100. The goal was to find out if one lens performed better in everyday use.

This study tested how comfortable two different daily soft contact lenses feel right after putting them in. 45 adults who already wear contacts and have mild to moderate nearsightedness rated each lens on a 0-100 comfort scale. The goal was to see if one lens feels better than th…

This study tested two types of soft contact lenses—Proclear 1 Day and MyDay sphere—to see which one feels more comfortable. 44 adults who already wear contact lenses rated comfort on a scale from 0 to 100. The goal was simply to compare the lenses, not to treat or cure any eye di…

This study tested two types of soft contact lenses—Myday Sphere and Myday Toric—in 32 people who already wear spherical lenses but have low astigmatism. Participants wore each lens type for one week and rated comfort on a 0-100 scale. The goal was to see if the toric lens offers …

This Phase 2 trial tested three different eye drop formulas—BRIMOCHOL, BRIMOCHOL F, and carbachol alone—to see if they could improve near vision in people with presbyopia (age-related difficulty seeing up close). The study enrolled 18 adults who received a single drop in each eye…

This study tested whether a special eye drop (esculin and digitalis glycosides) can improve near vision in people with presbyopia, the age-related difficulty focusing on close objects. 62 adults aged 40-55 took part. The goal was to see if the drops help the eye's focusing muscle…

This study compared two types of laser eye surgery—FS-LASIK and single-step TransPRK—for correcting mixed astigmatism, a condition where the eye's shape causes blurry vision at all distances. Thirty-nine people received one of the two procedures, and researchers measured their vi…

This study tested a new contact lens designed to help people with presbyopia (age-related blurry near vision) see clearly at both far and close distances, potentially reducing the need for bifocals or reading glasses. 78 adults aged 45 to 70 who already wear soft contact lenses t…

This study tested a special lens implant (EVO+ Visian ICL) to improve near vision in 41 adults with presbyopia, an age-related condition that makes it hard to see up close. The lens is placed behind the iris and in front of the eye's natural lens. Six months after surgery, most e…

This completed Phase 3 trial tested whether phentolamine eye drops (Nyxol) can improve near vision in people with presbyopia, the age-related loss of ability to focus on close objects. 569 adults aged 45 to 64 used the drops or a placebo once daily for 8 days. The main goal was t…

This Phase 3 trial tested Nyxol eye drops, alone or with low-dose pilocarpine, in 333 adults aged 40–64 with presbyopia (age-related difficulty seeing up close). The goal was to improve near vision without losing distance vision. Participants received drops and were measured afte…

This study tested a special type of artificial lens (TECNIS Eyhance IOL) in 62 adults aged 45-75 who had cataract surgery. The goal was to see how well the lens helps people see clearly at different distances, from close up to far away. Researchers measured vision at nine distanc…

This study looked at 40 people over 45 who had cataract surgery with a special lens that helps with both near and far vision. Half of them had the surgery with digital assistance, and half without. The goal was to see if the digital help led to better vision or more satisfaction …

This Phase 3 trial tested LNZ101 eye drops in 229 people aged 45-75 with presbyopia, a condition that makes it hard to see up close. The drops combine aceclidine and brimonidine to temporarily improve near vision. The main goal was to see if participants could read three lines be…

This study tested two types of soft contact lenses in 73 children and teenagers (ages 8 to 18) with nearsightedness. Researchers checked how well the lenses stayed centered on the eye and moved with each blink after at least three hours of wear. The goal was to see which lens per…

This completed study compared two types of soft toric contact lenses for people with astigmatism. Forty-two participants wore each lens briefly and rated them on comfort, vision, and overall satisfaction. The goal was to see which lens performed better in the short term.

This study tested whether a daily berry extract supplement (from aronia, honeyberry, and bilberry) could improve vision in 27 adults aged 50+ with presbyopia (age-related blurry near vision). Participants took the supplement or a placebo for 6 weeks each, with a 5-week break in b…

This study tested a low-energy femtosecond laser (the Perfector device) to treat presbyopia in 19 people who already had monofocal lens implants from cataract surgery. The goal was to improve near and intermediate vision without harming distance vision. Participants were measured…

This early-phase study tested the safety of PRO-201 eye drops (a low-dose atropine solution) in 29 healthy adults aged 18 to 35. The main goal was to see if the drops cause unexpected side effects or light sensitivity. Researchers also checked vision, eye pressure, and comfort. T…

This study looked at two different artificial lenses used during cataract surgery to see which one gives better vision at near, middle, and far distances. 80 adults with cataracts received one of the two lenses. The goal was to find out if one lens helps people see better without…

This study tested new multifocal contact lenses designed for people with both presbyopia (age-related blurry near vision) and astigmatism (blurry vision due to an irregularly shaped cornea). 95 habitual contact lens wearers wore the lenses for 30 days, and researchers measured ho…

This study tested whether a 'dynamic defocus' display mode can help reduce visual fatigue in adults who regularly use screens. 36 participants watched videos with different display settings, and researchers measured eye focus ability and tiredness. The goal is to find a simple wa…

This study tested a special lens implant (EVO+ Visian ICL) in 47 adults to correct or reduce nearsightedness, farsightedness, astigmatism, and age-related reading problems (presbyopia). The lens was placed inside the eye to improve vision at all distances without removing the nat…

This study tested two different lens approaches for cataract surgery: one group got two different extended-depth-of-focus lenses (one in each eye), and the other got the same trifocal lens in both eyes. The goal was to see which caused fewer halos and better vision. 36 adults hav…

This study tested two different trifocal lens implants used during cataract surgery to see which one gives better vision. 87 people who needed cataract surgery in both eyes received one type of lens in each eye. The main goal was to measure how clearly they could see letters on a…

This study tested how well DAILIES TOTAL1 daily disposable contact lenses work for people with myopia (nearsightedness) who use digital devices for at least 8 hours a day. 41 adults rated their comfort, dryness, and vision clarity after a day of screen use. The goal was to see if…

This study tested a new daily disposable contact lens designed for people with astigmatism (blurry vision from an irregularly shaped cornea) and presbyopia (age-related difficulty seeing up close). 176 adults aged 40-70 wore the lens for one week. Researchers measured how well th…

This study tested whether switching from Acuvue Oasys contact lenses to PRECISION7 lenses improves comfort and reduces dry eye symptoms. Seventy-one adults who were happy with their current lenses wore PRECISION7 lenses for two weeks. They completed surveys about their experience…

This study tested two different multifocal contact lenses in 106 people with presbyopia, an age-related condition that makes it hard to see up close. Participants wore each lens for a week to see how well they could see at different distances. The goal was to compare the performa…

This study tested whether a combination of two eye drops (Nyxol and pilocarpine) can help people with presbyopia—age-related difficulty seeing up close—read better without glasses. About 150 adults aged 40 to 64 took part. The main goal was to see how many people could read 15 or…

This completed study tested a new daily disposable contact lens called DSiHy for correcting nearsightedness (myopia). 134 adults who already wore contacts were randomly assigned to use either the new lens or a standard daily lens. The goal was to see if the new lens provides clea…

This study tested whether a program of eye exercises could improve visual function and quality of life in 40 adults with refractive errors like nearsightedness, farsightedness, or astigmatism. Participants did 20-minute sessions three times a week for eight weeks, plus home exerc…

This study tested whether using a red-light device twice a day for a month can reduce visual fatigue in people aged 40 and older with presbyopia (age-related difficulty seeing up close). Sixty-six participants either used the real device or a sham device. Researchers measured cha…

This early-phase study tested whether a new eye drop called NV701 works better than the existing drop Vuity for shrinking pupil size in people with presbyopia (age-related blurry near vision). Fifty-five adults aged 40-55 received one dose of each drop in different eyes. Research…

This study measured how three common eye surgeries—LASIK, PRK, and corneal cross-linking (CXL)—change the stiffness of the cornea. Using a device called Corvis ST, researchers assessed 150 adults who had undergone one of these procedures at least a month earlier. The goal was to …

This study investigates how low doses of atropine eye drops (0.01%, 0.02%, and 0.05%) affect pupil size and the eye's ability to focus in healthy adults aged 18 to 40. Researchers aim to compare different dosing methods and recovery times, and to see if iris color influences the …

This study examined 39 people with severe nearsightedness to see if lower levels of a natural eye pigment (macular pigment) are linked to tiny cracks in the back of the eye called lacquer cracks. These cracks can lead to vision loss. The researchers measured the pigment's optical…

This study checked if a smartphone app called VisionApp can accurately measure vision problems like nearsightedness and presbyopia (age-related reading difficulty). Sixteen adults aged 40 and older used the app at home, and their results were compared to standard eye exams. The g…

This study followed 248 children with nearsightedness who wore soft bifocal contact lenses for two years and then switched to regular lenses for a third year. Researchers measured eye growth, light exposure, and pupil responses to understand why some children's nearsightedness ge…

This study looked at how nearsightedness (myopia) affects the quality of life of children and adults. Researchers surveyed parents of nearsighted children and adults with long-term complications from myopia. The goal was to understand the real-world impact of the condition, not t…

This study looked at whether using eye drops to dilate (widen) the pupils before measuring vision leads to better eyeglass prescriptions for people with Down syndrome. 42 participants had their vision tested with and without dilation. The goal was to see which method gives sharpe…

This study tested four different approaches to find and treat eye diseases like cataracts, glaucoma, and diabetic retinopathy in communities in Nepal. Over 87,000 people aged 50 and older took part. The goal was to see which method—comprehensive screening, cataract camps, communi…

This study tested a new device called the EYESTAR 900, which uses light to take detailed measurements of the eye's shape. 29 people with healthy eyes, corneal scarring, or irregular astigmatism took part. The goal was to see how well the new scanner measures eye geometry compared…

This completed study looked at how satisfied 300 people were with their vision at least one year after having Wavelight LASIK surgery for nearsightedness (myopia). Researchers also checked for dry eye symptoms using standard questionnaires. The goal was to understand real-world p…

This study looked at data from 1100 people who had SMILE laser eye surgery to fix nearsightedness. Researchers used a computer model to predict how well patients would see one year after surgery. The goal was to see if the model could give more accurate results than the usual pla…

This study followed 609 nearsighted adults who had lens surgery to see if a natural eye change called posterior vitreous detachment (PVD) affects their risk of retinal detachment. Participants were grouped by whether they had PVD before surgery or not, and were monitored for up t…

This study compared two different optical devices that measure the eye before cataract or presbyopia surgery. 133 patients had their eyes measured with both devices to see if the measurements matched. The goal was to help doctors choose the best tool for planning lens implants.

This study tested a device called IOLMASTER 700 TK to see if it can more accurately measure the eye's curvature in people who had laser vision correction and now need cataract surgery. Researchers compared four different lens calculation methods in 155 adults. The goal was to imp…

This study looked at how light enters and focuses in the eyes of 23 nearsighted children. Researchers measured both central and side vision to better understand myopia. No treatment was given—the goal was simply to gather information.

This study looked at 52 soft contact lens wearers to see if a computer program (ImageJ) can measure eye redness more accurately than the standard grading system. The goal is to catch early signs of eye irritation. Participants wore lenses for two weeks and had their eyes checked …

This study tested how well a new device (ELITA) docks onto the eye for refractive error treatment. 55 adults participated to see if the docking procedure works correctly. The study did not provide treatment, only measured the device's performance.

This completed study looked at 100 people with low-to-moderate nearsightedness who chose either SMILE or LASEK laser eye surgery. Researchers measured contrast sensitivity and eye-brain signals to see how visual quality changed after surgery. The goal was to understand how age af…

This study used tiny temperature sensors hidden in glasses frames to track how often children wore their myopia-control spectacles. Fifty-three kids aged 6 to 15 who already used these glasses for at least three months took part. The goal was to understand real-world wearing patt…

This study tested if sending SMS reminders to parents helps children get follow-up eye care after a school vision screening. About 320 children aged 5-15 from two schools in Rawalpindi, Pakistan, were screened using a smartphone app. Those who needed further care were split into …

This completed study tested a virtual eye model system (VEMoS) to help personalize cataract and refractive surgery. Researchers collected eye measurements from over 500 participants, including those having surgery and those with healthy eyes. The goal was to find which measuremen…

This study looked at 41 adults aged 50-90 who had cataract surgery with a special lens that corrects astigmatism. Doctors compared two methods of marking the eye before placing the lens: a digital marker and a conventional manual marker. The goal was to see which method gives bet…

This study compared how well two types of toric contact lenses (Proclear Toric and Biofinity Toric) fit in people with astigmatism. Thirty-seven adults who already wear toric lenses tried each lens for 15 minutes. The goal was to see which lens had a better fit. The study is comp…