New eye drops could replace reading glasses for millions

NCT ID NCT05656027

Completed Symptom relief Sponsor: LENZ Therapeutics, Inc Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested an eye drop called LNZ101 to help people with presbyopia (age-related trouble seeing up close) read without glasses. 469 adults aged 45-75 received the drops, and researchers measured how many gained clear near vision without losing distance vision on the first day. The goal was to see if the drops are safe and effective for temporary symptom relief.

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Conditions

The condition(s) this trial relates to.

eye disorder myopia presbyopia refractive error

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

EYE DISEASES NEAR VISION PRESBYOPIA REFRACTIVE ERROR

Contacts and locations

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Locations

Site #101

Glendale, California, 91204, United States
Site #102

Mt. Dora, Florida, 32757, United States
Site #103

Kingston, Pennsylvania, 18704, United States
Site #104

Fargo, North Dakota, 58103, United States
Site #106

Chandler, Arizona, 85224, United States
Site #107

Petaluma, California, 94954, United States
Site #108

Pittsburg, Kansas, 66762, United States
Site #109

Littleton, Colorado, 80120, United States
Site #110

Garden Grove, California, 92843, United States
Site #111

Santa Barbara, California, 93105, United States
Site #112

Smyrna, Tennessee, 37167, United States
Site #116

Memphis, Tennessee, 38104, United States
Site #118

Rock Island, Illinois, 61201, United States
Site #119

San Antonio, Texas, 78229, United States
Site #121

Mesa, Arizona, 85202, United States
Site #122

Phoenix, Arizona, 85032, United States
Site #123

San Antonio, Texas, 78229, United States
Site #124

Phoenix, Arizona, 85053, United States
Site #125

Sun City, Arizona, 85351, United States
Site #126

Rancho Cordova, California, 95670, United States
Site #127

Overland Park, Kansas, 66210, United States
Site #128

Scottsdale, Arizona, 85260, United States
Site #129

Newport Beach, California, 92663, United States
Site #130

Azusa, California, 91702, United States
Site #131

Rochester, New York, 14618, United States

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