Presbyopia

This study is checking the long-term safety of the IC-8 Apthera lens, which is implanted during cataract surgery. It focuses on a common complication called posterior capsule opacification (PCO), where the lens capsule becomes cloudy. Researchers will follow 435 people for 24 mon…

This study compares two types of trifocal toric lens implants used during cataract surgery to correct both cataracts and astigmatism. About 138 adults with cataracts and regular astigmatism will receive one of the two lenses. The main goal is to see which lens provides better int…

This study tests new versions of Clareon Vivity Pro intraocular lenses (IOLs) to see if they improve vision better than current lenses. About 231 adults with cataracts in both eyes will receive one new lens and one current lens to compare results. The main goal is to measure how …

This study looks at whether people who already wear INFUSE One-Day multifocal contact lenses for presbyopia (age-related blurry near vision) feel more comfortable and see better after switching to DAILIES TOTAL1 multifocal lenses. About 30 satisfied lens wearers, aged 40 and olde…

This study tests a small device called the VisAbility™ Micro Insert System, which is placed in the eye to help people with presbyopia (age-related trouble seeing up close) read without glasses. It involves 33 adults aged 45 to 60 and will track safety and vision improvement over …

This study tests whether Total30 multifocal toric contact lenses are more comfortable and provide better vision than current lenses for people with presbyopia (age-related blurry near vision). 32 adults aged 40 and older who already wear toric contacts will try the new lenses for…

This study compares two daily disposable multifocal contact lenses for people with presbyopia, an age-related condition that makes it hard to see up close. About 35 adults who already wear soft contact lenses will test each lens for one week. The goal is to see which lens provide…

This study looks at how people with presbyopia (age-related blurry near vision) feel about wearing multifocal contact lenses compared to regular contact lenses plus reading glasses. About 30 adults aged 40 and older will try both options and report which they prefer. The goal is …

This study will test how comfortable and clear TOTAL30 Multifocal contact lenses feel after wearing them for up to 16 hours. About 36 adults who already wear multifocal contacts will rate their comfort and vision at several points during the day over one month. The goal is to see…

This study is testing a new type of daily disposable contact lens called UNICON. It will involve 35 adults who already wear soft contact lenses. Participants will wear the test lenses for up to 13 weeks to see if they are safe and comfortable for correcting nearsightedness.

This study screens people with eye diseases to see if they can join other research studies at the National Eye Institute. No treatment is given. Participants undergo eye exams, blood tests, and other procedures to diagnose or evaluate their condition. The goal is simply to determ…

This study tests a special camera that takes super-detailed pictures of the back of the eye (the retina). The goal is to see if this technology can find eye diseases earlier than standard methods. Up to 1,000 people aged 12 and older, with or without eye disease, will have their …

This study is developing imaging and computer simulation tools to predict how a person's cornea (the clear front part of the eye) will change after treatments like crosslinking for keratoconus or LASIK for vision correction. Researchers will take detailed images of the eyes of 60…

This study aims to learn more about eye diseases by observing and providing standard care to up to 1,000 people over 5 years. Participants receive regular eye exams, tests, and treatments as needed. The goal is to better understand how eye diseases progress and are inherited, not…

This study tests whether artificial intelligence can create simple summaries of eye doctor notes that are easier for patients to understand. About 460 English-speaking adults receiving eye care will get either standard notes or notes plus an AI-generated plain language summary. P…

This study looks at how different types of artificial lighting affect how well people see after having presbyopia (age-related blurry near vision) corrected with special extended-depth-of-focus lens implants. Researchers will measure the minimum light needed for clear distance vi…

This study tests a new 4D microscope-integrated OCT system for the first time in people during eye surgery. Researchers want to see if the system is easy to use, safe, and can clearly show eye structures. Five adults having eye surgery will take part. The goal is to improve imagi…

This study gathers standard eye movement and pupil data from 200 healthy volunteers, children, and people with eye or brain conditions using a VR headset called neos™. The headset shows images and tracks where participants look, how their pupils react, and how their eyes move. Th…

This study tests a new, more comfortable eye camera (WiSLO) designed for children and adults. Researchers want to see if it takes better pictures and is less bothersome than current cameras. About 42 people with or without eye disease will have their eyes photographed with both t…