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Overnight lenses reshape the eye: a closer look at vision quality

NCT ID NCT06775509

Disease control Sponsor: Institut Investigacio Sanitaria Pere Virgili Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 21, 2026 · Last updated Jul 22, 2026 · Updated 1 time

Summary

This study examines how wearing Ortho-K contact lenses overnight changes the optical quality of the cornea in children and young adults aged 8 to 21 with mild to moderate nearsightedness and astigmatism. Participants wear the lenses for 8–10 hours each night, and researchers measure changes in corneal aberrations after 30 days. The goal is to better understand how these lenses affect vision sharpness beyond standard eye chart tests.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Ortho-K contact lenses worn overnight to reshape the cornea and temporarily correct myopia
What this could lead to
If successful, this could help refine Ortho-K lens designs to improve visual quality and slow myopia progression in young people.
What could go wrong
This is a small, early-stage study focused on optical measurements, not long-term outcomes. Results may not apply to all lens types or patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

23 people

The number who actually took part.

Started

Jan 2025

Finished

Feb 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

12 to 21 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients between 8 and 21 years old. Those who accept to participate in the study. The use of Ortho-K lenses for 8 to 10 hours per night, once the risks and benefits of using Ortho-K have been explained. * Refractive error of myopia between -1.00 and -5.00 diopters (D) with astigmatism of 1.50 D or less, with-the-rule. * Best-corrected visual acuity of 20/20 or better before treatment. * Ortho-K lens centered or decentered by no more than 0.5 mm radially, determined by slit-lamp examination. Exclusion Criteria: * History of hard contact lens use and contraindications for ocular and systemic Ortho-K, determined by a routine examination. * Patients who have previously undergone any refractive modulation procedure. * Patients with any corneal pathology, dry eye, glaucoma, retinal pathology, strabismus, ptosis, amblyopia, history of ocular allergy, or infection.

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Conditions

The condition(s) this trial relates to.

astigmatism myopia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Astigmatism Myopia (disorder)

Contacts and locations

Locations

  • Clínica Licari Vision

    Tarragona, Tarragona, 43001, Spain

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