New eye drop takes on vuity in Pupil-Size showdown

NCT ID NCT06783686

Completed Symptom relief Sponsor: Novus Vision LLC Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This early-phase study tested whether a new eye drop called NV701 works better than the existing drop Vuity for shrinking pupil size in people with presbyopia (age-related blurry near vision). Fifty-five adults aged 40-55 received one dose of each drop in different eyes. Researchers measured pupil size over 8 hours to see which drop caused more constriction.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Pilocarpine 1.25% eye drops
What this could lead to: If NV701 works better than Vuity, it could offer a more effective option for temporarily improving near vision in people with presbyopia.
What could go wrong: This is a very early, small study (55 people) testing only a single dose. It may not show a meaningful difference, and results may not apply to long-term use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Miosis presbyopia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PUPIL CONSTRICTION

Contacts and locations

Locations

Arizona Eye Center

Chandler, Arizona, 85224, United States
Global Research Management, Inc

Glendale, California, 91204, United States

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