Eye drops could replace reading glasses for presbyopia
NCT ID NCT04774237
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This Phase 2 trial tested three different eye drop formulas—BRIMOCHOL, BRIMOCHOL F, and carbachol alone—to see if they could improve near vision in people with presbyopia (age-related difficulty seeing up close). The study enrolled 18 adults who received a single drop in each eye. Researchers measured how many people gained at least 15 letters on a near vision chart without losing distance vision. This is an early, small study to check safety and effectiveness.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
BRIMOCHOL (carbachol/brimonidine tartrate) eye drops
What this could lead to
If successful, this could lead to a non-surgical eye drop that temporarily improves near vision for people with presbyopia.
What could go wrong
This is a very small Phase 2 trial with only 18 people, so results may not apply to everyone. The effect is temporary and may not work for all types of presbyopia.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Eye Research Foundation
Newport Beach, California, 92663, United States
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Global Research Management, Inc.
Glendale, California, 91204, United States
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Total Eye Care, PA
Memphis, Tennessee, 38119, United States