Eye drops could replace reading glasses for presbyopia

NCT ID NCT04774237

Completed Symptom relief Sponsor: Visus Therapeutics Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This Phase 2 trial tested three different eye drop formulas—BRIMOCHOL, BRIMOCHOL F, and carbachol alone—to see if they could improve near vision in people with presbyopia (age-related difficulty seeing up close). The study enrolled 18 adults who received a single drop in each eye. Researchers measured how many people gained at least 15 letters on a near vision chart without losing distance vision. This is an early, small study to check safety and effectiveness.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: BRIMOCHOL (carbachol/brimonidine tartrate) eye drops
What this could lead to: If successful, this could lead to a non-surgical eye drop that temporarily improves near vision for people with presbyopia.
What could go wrong: This is a very small Phase 2 trial with only 18 people, so results may not apply to everyone. The effect is temporary and may not work for all types of presbyopia.

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Conditions

The condition(s) this trial relates to.

presbyopia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PRESBYOPIA

Contacts and locations

Locations

Eye Research Foundation

Newport Beach, California, 92663, United States
Global Research Management, Inc.

Glendale, California, 91204, United States
Total Eye Care, PA

Memphis, Tennessee, 38119, United States

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