New eye drop combo shows promise for reading without glasses

NCT ID NCT04675151

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a combination of two eye drops (Nyxol and pilocarpine) can help people with presbyopia—age-related difficulty seeing up close—read better without glasses. About 150 adults aged 40 to 64 took part. The main goal was to see how many people could read 15 or more extra letters on an eye chart one hour after using the drops, compared to their starting vision.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

presbyopia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Clinical Site 1

    Memphis, Tennessee, 38119, United States

  • Clinical Site 10

    Roswell, Georgia, 30041, United States

  • Clinical Site 11

    Maitland, Florida, 32751, United States

  • Clinical Site 12

    Laguna Hills, California, 92653, United States

  • Clinical Site 13

    Crystal River, Florida, 34461, United States

  • Clinical Site 14

    Fargo, North Dakota, 58103, United States

  • Clinical Site 15

    Powell, Ohio, 43065, United States

  • Clinical Site 16

    Poughkeepsie, New York, 12603, United States

  • Clinical Site 18

    St Louis, Missouri, 63101, United States

  • Clinical Site 2

    Athens, Ohio, 45701, United States

  • Clinical Site 3

    Pittsburg, Kansas, 66762, United States

  • Clinical Site 4

    Warwick, Rhode Island, 02888, United States

  • Clinical Site 5

    Longwood, Florida, 32779, United States

  • Clinical Site 6

    Newport Beach, California, 92663, United States

  • Clinical Site 7

    Cleveland, Ohio, 44115, United States

  • Clinical Site 8

    Sarasota, Florida, 34239, United States

  • Clinical Site 9

    Cincinnati, Ohio, 45242, United States