New eye drop combo may help you ditch reading glasses

NCT ID NCT04675151

First seen Nov 01, 2025 · Last updated May 04, 2026 · Updated 33 times

Summary

This study tested whether combining two eye drops (Nyxol and pilocarpine) can improve close-up vision in people with presbyopia, the age-related difficulty seeing things up close. About 150 adults aged 40 to 64 took part. The main goal was to see how many could read 15 more letters on an eye chart one hour after using the drops, compared to a placebo.

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Contacts and locations

Locations

  • Clinical Site 1

    Memphis, Tennessee, 38119, United States

  • Clinical Site 10

    Roswell, Georgia, 30041, United States

  • Clinical Site 11

    Maitland, Florida, 32751, United States

  • Clinical Site 12

    Laguna Hills, California, 92653, United States

  • Clinical Site 13

    Crystal River, Florida, 34461, United States

  • Clinical Site 14

    Fargo, North Dakota, 58103, United States

  • Clinical Site 15

    Powell, Ohio, 43065, United States

  • Clinical Site 16

    Poughkeepsie, New York, 12603, United States

  • Clinical Site 18

    St Louis, Missouri, 63101, United States

  • Clinical Site 2

    Athens, Ohio, 45701, United States

  • Clinical Site 3

    Pittsburg, Kansas, 66762, United States

  • Clinical Site 4

    Warwick, Rhode Island, 02888, United States

  • Clinical Site 5

    Longwood, Florida, 32779, United States

  • Clinical Site 6

    Newport Beach, California, 92663, United States

  • Clinical Site 7

    Cleveland, Ohio, 44115, United States

  • Clinical Site 8

    Sarasota, Florida, 34239, United States

  • Clinical Site 9

    Cincinnati, Ohio, 45242, United States

Conditions

Explore the condition pages connected to this study.