New eye drop combo shows promise for reading without glasses
NCT ID NCT04675151
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a combination of two eye drops (Nyxol and pilocarpine) can help people with presbyopia—age-related difficulty seeing up close—read better without glasses. About 150 adults aged 40 to 64 took part. The main goal was to see how many people could read 15 or more extra letters on an eye chart one hour after using the drops, compared to their starting vision.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Clinical Site 1
Memphis, Tennessee, 38119, United States
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Clinical Site 10
Roswell, Georgia, 30041, United States
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Clinical Site 11
Maitland, Florida, 32751, United States
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Clinical Site 12
Laguna Hills, California, 92653, United States
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Clinical Site 13
Crystal River, Florida, 34461, United States
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Clinical Site 14
Fargo, North Dakota, 58103, United States
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Clinical Site 15
Powell, Ohio, 43065, United States
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Clinical Site 16
Poughkeepsie, New York, 12603, United States
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Clinical Site 18
St Louis, Missouri, 63101, United States
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Clinical Site 2
Athens, Ohio, 45701, United States
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Clinical Site 3
Pittsburg, Kansas, 66762, United States
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Clinical Site 4
Warwick, Rhode Island, 02888, United States
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Clinical Site 5
Longwood, Florida, 32779, United States
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Clinical Site 6
Newport Beach, California, 92663, United States
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Clinical Site 7
Cleveland, Ohio, 44115, United States
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Clinical Site 8
Sarasota, Florida, 34239, United States
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Clinical Site 9
Cincinnati, Ohio, 45242, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a new contact lens sharpen both near and far vision for aging eyes?
- A tiny corneal pocket may restore Close-Up vision — no glasses needed
- Laser eye surgery may offer a One-Time fix for reading glasses — a trial puts it to the test
- Eye drops may offer a new way to read without glasses — a trial puts them to the test
- Tiny corneal lens holds up after 4 years for near vision
- Could a micro implant replace reading glasses?