Nasal disorder

This early-stage study tests a new vaccine called PollenVax for people with moderate to severe mugwort pollen allergy. The main goal is to see if the vaccine is safe and tolerable in 30 adults aged 18 to 65. Participants receive four shots of either the vaccine or a placebo, and …

This study tests whether a nasal spray containing adelmidrol can reduce inflammation and shrink nasal polyps in people with chronic sinusitis. Participants are adults aged 18 to 70 who are scheduled for sinus surgery. Half receive standard care plus the adelmidrol spray, while th…

This study looked at 84 people with severe allergic rhinitis (constant sneezing, runny nose, itching, stuffiness) that didn't improve with usual treatments. Researchers compared three procedures that target the nerve in the nose: surgical cutting, radiofrequency, and surface cobl…

This study tested a device called NEUROMARK in 80 adults with chronic rhinitis (long-term stuffy or runny nose). The device uses radiofrequency energy to disrupt nerves in the nose that trigger symptoms. The goal was to see if it safely reduces nasal symptoms like congestion and …

This study tested whether combining two FDA-approved cancer drugs, cetuximab and nivolumab, could help people with advanced head and neck cancer that has returned or spread. A total of 95 participants received the drug combination to find the best dose and see if it improves surv…

This study looked at whether rinsing the nose with diluted povidone-iodine (a common antiseptic) after sinus surgery helps people with chronic sinusitis recover better than standard saline or mucomyst rinses. Forty-eight adults who had sinus surgery used one of the three rinses d…

This study tested whether a dietary supplement called Imunoglukan P4H® (made from pleuran, a mushroom extract, plus vitamin C) could help people with chronic sinusitis. 85 patients over age 12 took the supplement alongside standard treatments like nasal sprays and saline rinses. …

This study tested a type of allergy immunotherapy (Clustoid® Max Forte) in 140 people aged 5 to 65 with dust mite allergies. The goal was to see if it reduces allergy and asthma symptoms and the need for medication over one year. Results were measured by symptom scores and medica…

This study tested a dietary supplement containing immune-supporting nutrients and postbiotics in 40 children aged 5–12 with asthma and/or allergic rhinitis. The goal was to see if the supplement could improve symptom control over 6 months. Researchers also looked at changes in im…

This study looked at how dupilumab, a drug that blocks certain immune signals, improves smell in adults with chronic sinusitis and nasal polyps. Researchers measured changes in inflammation in the smell region using CT scans, endoscopy, and mucus samples over three months. The go…

This phase 3 trial tested tezepelumab, a biologic drug given as a shot, in 416 adults with severe chronic sinusitis and nasal polyps. Participants received either tezepelumab or a placebo, plus a standard nasal steroid spray. The study measured changes in polyp size and nasal con…

This study tested two ways to pull the upper jaw forward in 40 children aged 7-13 with underbite. One method used a traditional face mask attached to teeth, the other used tiny screws placed in the cheekbone. Both followed a special expansion protocol. The goal was to see which a…

This early-phase trial tested a combination of two drugs — IRX-2 and durvalumab — in 19 people with advanced head and neck cancer that could not be cured by standard treatments. The goal was to see if the combination was safe and could boost the immune response inside tumors. The…

This phase 3 trial tested a biologic drug called depemokimab in 276 adults with chronic sinusitis and nasal polyps. Participants received either the drug or a placebo as an injection under the skin. The study measured changes in polyp size and nasal blockage over 52 weeks to see …

This study compared two types of sinus surgery for people with chronic sinusitis and nasal polyps that involve a type of inflammation called eosinophilic. One surgery (MRESS) removes more tissue, including the middle turbinate, while the standard surgery (FESS) preserves it. The …

This study tested whether theophylline, an asthma drug, could help people who lost their sense of smell after a head injury. 158 patients who had not improved with standard treatments took theophylline or a placebo, plus did smell training for 6 months. The goal was to see if the…

This completed trial tested whether a gelatin sponge works as well as a bone matrix for lifting the sinus floor during dental implant placement. Fourteen patients with low bone height in the upper jaw received one of the two materials. The study measured bone gain and implant sta…

This Phase 3 trial tested a biologic drug called depemokimab in 264 adults with chronic sinusitis and nasal polyps. Participants received either the drug or a placebo as a shot under the skin. The study measured changes in polyp size and nasal blockage over 52 weeks. The goal is …

This completed study tested whether facial images and voice recordings can help screen for allergic rhinitis (hay fever). Researchers collected photos and voice samples from 1500 people with chronic rhinitis, then compared them to standard allergy tests. The goal was to build a p…

This study looked at whether nasal drops made from Pistacia lentiscus oil (a natural plant oil) can help prevent chronic sinusitis from coming back. 100 adults with frequent sinus infections were followed for 12 months. One group used the oil drops plus a saltwater rinse, while t…

This study tests whether a probiotic gummy containing Weizmannia coagulans BC99 can reduce symptoms of allergic rhinitis (hay fever) in children aged 4 to 14. Over 8 weeks, half the children receive the probiotic gummy and half receive a placebo. Researchers track changes in nasa…

This study tested whether a numbing injection behind the nose (sphenopalatine ganglion block) could reduce confusion and agitation after sinus surgery. 100 adults received either the nerve block or a placebo. The goal was to see if the block helped patients wake up more calmly an…

This study tested whether adding thread embedding acupuncture (TEA) to standard steroid nasal spray helps people with allergic rhinitis. 64 adults took part. The goal was to see if the combination reduces symptoms like sneezing and stuffy nose better than the spray alone, and whe…

This study tested a device called NEUROMARK that uses radiofrequency energy to disrupt nerves in the nose. It included 36 adults with moderate to severe chronic rhinitis. The goal was to see if the procedure safely reduces symptoms like runny nose and congestion over 3 months.

This study tested whether a natural supplement called ultramicronized palmitoylethanolamide (umPEA) can improve smell, taste, and other sensory issues in children with autism. Eighty children took either umPEA or a standard treatment (probiotics plus omega-3) for six months. Rese…

This study tested whether rinsing the sinuses with hot saline (50°C) during surgery for chronic sinusitis reduces bleeding and improves the surgeon's view. 59 adults were split into three groups: hot saline, room-temperature saline, or no rinse. The goal was to see if the hot rin…

This study tested whether a home-use light device (rhinophototherapy) can reduce nasal inflammation and allergy symptoms as well as a standard steroid spray. Thirty-five adults with allergic rhinitis used either the light device for 4.5 minutes three times daily or a steroid spra…

This study looked at 52 adults with EGPA (a rare inflammatory disease) and severe chronic sinusitis with nasal polyps. They received mepolizumab 300 mg every 4 weeks. The goal was to see if the drug reduces polyp size and improves symptoms like nasal congestion and sense of smell…

This study tested whether adding a decongestant nasal spray for the first 5 days to standard steroid spray treatment helps children with persistent allergic rhinitis feel better faster. 76 children aged 4-18 were randomly assigned to receive either steroid spray alone for 4 weeks…

This study tested two drugs, dexmedetomidine and nitroglycerin, to see which one better reduces bleeding during functional endoscopic sinus surgery (FESS). 66 adults having elective FESS were randomly assigned to receive one of the drugs to lower blood pressure and improve the su…

This study tested two different nasal packs used after nose surgery to see which one patients liked better and which led to better healing. Twenty adults who had nasal surgery received either a VELNEZ or NASOPORE pack. Researchers checked for pain, bleeding, and how well the pack…

This completed trial tested whether a probiotic called Bifidobacterium longum ES1, or its heat-treated version, could reduce symptoms of allergic rhinitis (hay fever) in 72 adults with moderate-to-severe dust mite allergies. Participants took daily capsules for several weeks and …

This study tested an investigational treatment called PQ Grass 27600 SU in 119 adults with seasonal grass pollen allergies (hay fever). The goal was to see if it could reduce allergy symptoms and the need for relief medications during peak grass pollen season. Participants receiv…

This study tested an experimental nasal spray called INI-2004 in 78 adults with ragweed allergies. Participants received either the spray or a placebo once a week for four weeks, then spent time in a room filled with ragweed pollen to see if symptoms improved. The goal was to che…

This study looked at whether taking a grass pollen tablet (SLIT) together with the drug dupilumab for 2 years can help adults with moderate to severe hay fever tolerate grass pollen better, even after stopping treatment. About 199 participants were involved. The main goal was to …

This study tested different doses of melatonin (3, 5, and 10 mg) compared to a placebo in 160 adults undergoing sinus surgery. The goal was to see which dose best reduces anxiety and pain while keeping heart rate and blood pressure stable. Results could help doctors choose the ri…

This study tested whether adding a gentle hands-on therapy called craniosacral osteopathic treatment to standard care can improve symptoms and quality of life for people with chronic sinusitis. Fifty adults with the condition were randomly assigned to receive either standard medi…

This study tested a nitric oxide nasal spray against a saline placebo in 162 adults with recurrent acute sinusitis. Participants used the spray at the first sign of a new episode for two weeks. The goal was to see if the nitric oxide spray speeds up symptom relief and reduces the…

This study tested a nasal spray made from pistacia lentiscus oil (Bactorinol) in 120 adults with vasomotor rhinitis, a chronic condition causing nasal congestion and runny nose. Participants used the spray or a saline placebo for 20 days. The goal was to see if the oil spray impr…

This small study tested a herbal tea made from berry and mango leaves in 10 adults with acute sinusitis. Participants drank the tea three times a day alongside their usual care for one month. Researchers measured changes in quality of life using a standard symptom questionnaire. …

This pilot study tested whether chewing flavored gum twice a day for 12 weeks could help people recover their sense of smell and taste. Thirty adults with smell or taste loss were split into three groups: one chewed flavored gum, one smelled liquid flavors, and one waited. The st…

This completed trial tested the NEUROMARK device, which uses radiofrequency to disrupt nerves in the nose, against a sham (fake) procedure in 132 adults with chronic rhinitis. The goal was to see if the device could reduce symptoms like runny nose and congestion by at least 30% a…

This study tested Xolair (omalizumab) in 50 teenagers aged 12 to 17 with severe seasonal allergic rhinitis (hay fever) that standard treatments couldn't control. Researchers tracked side effects and how much symptoms improved. The goal was to see if Xolair is safe and effective i…

This small study tested whether acupuncture can relieve nasal congestion in people with allergic rhinitis. Eleven adults received either acupuncture or a standard nasal spray for 6 weeks. The goal was to see if acupuncture offers a safe, side-effect-free option for stuffy noses.

This study looked at two methods to treat concha bullosa, a condition where the middle turbinate in the nose is enlarged and can block sinuses. 62 adults with chronic sinusitis were randomly assigned to have the turbinate crushed or partially removed during sinus surgery. After o…

This study tested whether a supplement called M-Gard can help relieve symptoms of seasonal grass pollen allergies (hay fever). Twenty healthy adults with a history of grass allergies took M-Gard or a placebo in a crossover design. Researchers measured symptom severity like nasal …

This study tested the safety and effectiveness of Allegra D (fexofenadine plus pseudoephedrine) in 203 people aged 12 and older with allergic rhinitis. Participants took the medication for up to 13 days, and researchers tracked side effects and symptom improvement using nasal and…

This study looked at whether smell training with scented oils can help people regain their sense of smell after endoscopic skull base surgery. 41 adults with benign skull base tumors participated. Half used scented sticks and half used unscented sticks for training. Researchers m…

This study tested a new drug called CYR-064 in 151 adults aged 18-70 who have a reduced sense of smell (hyposmia). The goal was to see if the drug is safe and if it can improve smell and taste over 24 weeks compared to a placebo. Participants had no other nasal issues like polyps…

This study tested an experimental implant called LYR-210 in 182 adults with long-term sinus inflammation (chronic rhinosinusitis). The goal was to see if it could reduce key symptoms like nasal congestion, discharge, and facial pain better than a placebo. Participants received th…

This study tested a gel called PuraSinus to see if it makes follow-up cleanings after sinus surgery less painful. 30 adults with chronic sinus disease took part. The gel was compared to standard nasal dressings. The goal was to reduce pain and discomfort during these cleanings.

This pilot study tested whether a stellate ganglion block—a numbing injection near a nerve cluster in the neck—can help people who lost their sense of smell after COVID-19. Twenty adults with smell problems lasting at least a year received the injection. Researchers measured chan…

This study tested a new drug called BLU-808 in 21 adults with ragweed allergies. The goal was to see if it is safe and helps reduce sneezing, runny nose, and itchy eyes caused by ragweed pollen. Participants were exposed to ragweed in a special chamber to measure the drug's effec…

This Phase 2 trial tested an injection called TQC2938, a humanized monoclonal antibody, in 136 adults with seasonal allergic rhinitis. All participants also used a standard nasal spray. The study measured how well the injection reduced nasal symptoms like sneezing and congestion …

This study tested whether apple fruit extract, which has antioxidant and anti-inflammatory properties, could improve symptoms of allergic rhinitis (hay fever). Forty adults with persistent allergies received either standard treatment plus apple extract or standard treatment alone…

This study tested whether Ectoin allergy nasal spray and eye drops can relieve symptoms of hay fever (runny nose, sneezing, itchy eyes) better than a placebo. 46 adults with ragweed allergies were exposed to pollen in a special chamber. Researchers measured symptom scores and nas…

This study tested whether an ectoine nasal spray works better than a cromoglycic acid spray for easing allergic rhinitis symptoms like a stuffy nose, runny nose, and sneezing. Fifty adults with proven allergies used one of the two sprays for 14 days. Doctors and patients rated ho…

This study tested whether Ectoin nasal spray helps relieve symptoms of acute sinusitis compared to another medication (Sinupret forte). 66 adults used the spray or took the other drug for 14 days. Doctors checked symptoms at day 7 and day 14, and patients kept a daily diary. The …

This early-stage study tested a new drug called INI-2004 in 68 healthy people and those with ragweed allergies. The goal was to check safety and how well it reduces nasal symptoms like sneezing and congestion. Researchers gave single or multiple doses and monitored side effects a…

This early-stage trial tested the safety and tolerability of a new corticosteroid nasal spray called PA9159 in 36 healthy Chinese adults. Participants received either a single dose or seven daily doses of the spray, or a placebo. The goal was to find the maximum safe dose and see…

This study tested a drug called omalizumab in 337 adults and teens with severe Japanese cedar pollen allergy (hay fever) that standard medicines couldn't control. Participants received either omalizumab or a placebo on top of their usual allergy treatments for 12 weeks. The goal …

This study tested two ways to remove bone during a minimally invasive sinus surgery called the prelacrimal approach. One method uses a modern ultrasonic device (piezosurgery), the other uses a traditional hammer and chisel. The trial included 40 adults with various non-cancerous …

This study tested whether the drug TAU-284 (bepotastine besilate) can reduce sneezing, runny nose, and congestion in children aged 7 to 15 with perennial allergic rhinitis (year-round nasal allergies). In a double-blind, placebo-controlled design, 473 children took either the dru…

This study tested whether a budesonide nasal rinse (a steroid) could improve smell loss in 120 adults who still had trouble smelling 30 days after a mild COVID-19 infection. Participants used the rinse twice daily for 30 days, along with smell training. The goal was to see if mor…

This study tested a medicine called TAU-284 in 490 children aged 7 to 15 who have year-round nasal allergies. The goal was to see if it reduces sneezing, runny nose, and congestion better than a placebo. The trial was completed and focused on symptom relief, not a cure.

This study tested the long-term safety and effectiveness of TAU-284 (bepotastine besilate) in 58 children aged 7 to 15 with perennial allergic rhinitis (year-round nasal allergies). Over 12 weeks, researchers tracked side effects and changes in sneezing, runny nose, and congestio…

This study tested whether injecting the numbing drug ropivacaine into the nose can reduce pain after endoscopic sinus surgery. 184 adults having sinus surgery were randomly given either ropivacaine or a saltwater placebo injection. The main goal was to measure pain intensity and …

This study tested a new drug called LP-003 in 180 adults with moderate to severe seasonal allergic rhinitis (hay fever) that wasn't well controlled by usual treatments like antihistamines or nasal sprays. LP-003 is an antibody that blocks IgE, a key driver of allergic reactions, …

This early-stage study tested a single dose of the investigational drug MT-2990 in 75 adults with seasonal allergic rhinitis triggered by Japanese cedar pollen. The main goals were to check the drug's safety, how the body processes it, and whether it can reduce allergy symptoms w…

This study tested a medication called STALORAL Birch 300 IR in 553 children aged 5 to 17 with birch pollen allergies. The goal was to see if it safely reduces symptoms like sneezing, runny nose, and itchy eyes during pollen season. Participants received the treatment or a placebo…

This study looked at whether children with year-round allergic rhinitis can use a nasal steroid spray only when symptoms bother them, instead of every day. Sixty-eight children aged 6 to 18 were randomly assigned to either daily use or as-needed use of fluticasone furoate spray. …

This study tested an experimental drug called brensocatib in 288 adults with long-term sinus inflammation but no nasal polyps. Participants took either 10 mg, 40 mg, or a placebo daily for 24 weeks. The goal was to see if the drug could improve daily symptoms like congestion, run…

This study tested whether a stellate ganglion block (an injection near nerves in the neck) can improve distorted sense of smell (parosmia) caused by COVID-19. 48 adults with long-term smell issues after COVID took part. Half received the nerve block, half got a placebo (saline). …

This Phase 2 study tested dupilumab (Dupixent) in 33 adults with chronic sinusitis but no nasal polyps. Participants received injections every two weeks for six months. The main goal was to see if the drug improves sinus symptoms and quality of life compared to a placebo.

This completed study tested whether probiotic gummies can relieve allergic rhinitis symptoms in children aged 4 to 14. Over 56 days, 72 kids took either the probiotic or a placebo, and researchers tracked nasal symptoms, quality of life, and gut health. The goal was to see if pro…

This study tested whether a low dose of IL-2 (a protein that helps regulate the immune system) could reduce nasal symptoms in people with birch pollen allergy. Twenty-four adults with a history of seasonal allergies received either the drug or a placebo over several months. The g…

This study tested a nasal spray called AD17002 in 48 adults with house dust mite allergic rhinitis. The goal was to see if it is safe and can reduce symptoms like sneezing, runny nose, and congestion. Participants received either the spray or a placebo, and researchers monitored …

This study tested two drugs used to reverse muscle relaxants after surgery: sugammadex and a combination of neostigmine and glycopyrrolate. The goal was to see which one better prevents urinary retention in 124 patients having ear, nose, or throat surgery who were at high risk du…

This study tested whether a nanoemulsified sesame oil nasal spray can improve symptoms and healing after sinus surgery in people with chronic sinusitis. Sixty patients used different nasal solutions after surgery, and researchers measured symptom scores and endoscopic healing. Th…

This completed trial tested a wearable headband called Sonu that uses sound waves to relieve moderate to severe nasal congestion in children aged 12 to 21. The device works by sending gentle vibrations through the skull to clear the nasal passages. Researchers measured safety and…

This study tested whether taking the allergy drug fexofenadine for two days before ragweed season can reduce symptoms like sneezing and runny nose. 95 adults with ragweed allergies were randomly given either fexofenadine or a placebo. Researchers measured nasal symptoms over six …

This study tested whether adding the sedative drug dexmedetomidine to anesthesia improves the view for surgeons during endoscopic sinus surgery. Fifty adults with rhinosinusitis were enrolled. The goal was to see if the drug could make the surgical field clearer, potentially maki…

This study tested whether scented nose plugs could make smell training more effective for people who lost their sense of smell after a virus like COVID-19. 120 adults with reduced smell were split into two groups: one did regular smell training at home, and the other used scented…

This study investigates whether spores from birch rust fungi trigger seasonal allergies in autumn. Researchers will compare 30 people with suspected birch rust allergy to 15 non-allergic controls, tracking symptoms and spore levels. The goal is to understand a possible cause of a…

This completed study looked at over 107,000 patients in Germany to understand the long-term side effects of systemic steroids (corticosteroids) used for conditions like asthma, COPD, and arthritis. Researchers compared patients who took steroids with those who did not, tracking r…

This study looked at different types of immune cells (eosinophils) in the blood of people with asthma, chronic sinusitis with nasal polyps, or both, compared to healthy volunteers. The goal was to find patterns that could help doctors choose the best targeted therapy for each pat…

This study looked at whether using computer-assisted navigation during sinus surgery helps people with nasal polyps. Researchers compared surgery with and without this technology in 40 patients. They tracked how often polyps came back and how many complications occurred.

This study looked at 176 people who had COVID-19 and were having problems with smell, taste, or saliva. Researchers tested their senses and tried smell training as a way to help. The goal was to better understand these long-lasting symptoms and how to manage them.

This small pilot study tested a new way to place dental implants in the upper jaw when there is not enough bone height. Surgeons used a special drill and a tiny camera to watch the sinus membrane during the procedure. The goal was to see how often the membrane gets torn, which ca…

This completed study used artificial intelligence to examine electronic health records from 10,000 head and neck cancer patients. The goal was to create models that can predict the risk of cancer coming back or progressing, and to identify which patients might live longer after i…

This study looked for hidden immune system problems in adults who get frequent or severe bacterial infections, like pneumonia or meningitis. Researchers screened 120 adults aged 18-65 to see how many had an undiagnosed primary immunodeficiency. The goal was to find out if these c…

This completed study looked at whether substances in nasal fluid can help doctors objectively measure the severity of respiratory conditions like asthma, COPD, hayfever, and sinusitis. Researchers collected samples from 111 adults (including healthy volunteers) using a small nasa…

This study looked at gene activity in cells from the nose and lungs of 44 healthy and allergic adults. The goal was to understand how allergies change these cells and why the nose and lungs react differently. Researchers hope this knowledge will lead to better treatments for alle…

This study surveyed 500 parents of children with asthma or allergic rhinitis to see how much they know about air quality and pollution. The goal was to understand their awareness, knowledge, and protective behaviors. The results will help design better education and prevention pr…

This study tested whether a French translation of the SN-5 questionnaire, which measures quality of life in children with chronic rhinosinusitis, works as well as the original English version. Researchers asked 89 children (ages 2–12) and their parents to fill out the questionnai…

This study looked at whether a home visit by an environmental counselor can improve the quality of life for children with asthma or allergic rhinitis. Researchers checked the children's health at the start and again six months after the visit using standard questionnaires. The st…

This completed Phase 1 study tested whether two substances in the blood (sST2 and miR-223) can help predict how well patients with dust mite allergies respond to a six-month course of under-the-tongue immunotherapy (SLIT). Fifty-four patients with moderate-to-severe allergic rhin…

This study checked how common smell and taste problems are in 51 people with cardiac amyloidosis, a rare disease where abnormal proteins build up in the heart. Researchers used a simple smell test called Sniffin' Sticks to measure these senses. The goal was to see if these issues…

This study tested a program to help doctors prescribe antibiotics more appropriately for common childhood infections like earaches, sore throats, and sinusitis. Over 1,000 doctors took part, receiving online training, personalized feedback on their prescribing habits, and support…

This study looked at how the body naturally stops allergic inflammation after being exposed to grass pollen. Researchers measured specific molecules in the nose that help control and resolve the allergic response. Twenty adults with grass pollen allergies participated. The goal w…

This study followed 215 people with chronic sinusitis who received a corticosteroid-releasing sinus stent during sinus surgery. Researchers tracked safety and symptom changes over 6 to 12 months using a standard symptom questionnaire. The goal was to confirm the stent's long-term…

This study looked at 101 adults who had weight-loss surgery at least three months earlier. Researchers asked about changes in taste and smell, and how those changes relate to hunger and diet quality. The goal is to understand whether sensory shifts make it harder to eat well afte…

This study looked at how mepolizumab, a biologic drug, changes inflammation in people with severe eosinophilic asthma. Researchers measured immune and metabolic markers in the nose, lungs, and blood of 15 adults. The goal was to better understand the drug's full impact beyond jus…

This study looked at how a molecule called IL-5 affects different cells in the sinuses of people with nasal polyps and a related condition called aspirin-exacerbated respiratory disease. Researchers analyzed tissue samples from 30 participants to understand how IL-5 contributes t…

This study looked at 134 adults with chronic sinusitis to see if sleep problems and daytime tiredness predict declines in thinking skills and daily functioning. Participants filled out questionnaires about their symptoms and quality of life. The goal was to better understand how …

This study observed how private pediatricians in France manage allergic rhinitis (hay fever) in children under 18. Over 1,000 children participated, and researchers collected data on current treatment practices, including how many kids might be eligible for allergy immunotherapy.…

This study looked at two methods to widen the upper jaw in adults whose jawbone has fully grown. One method uses small screws anchored in the roof of the mouth, and the other adds tiny bone punctures to help the jaw separate more easily. Twenty-four adults took part, and the resu…

This study aimed to find the right strength of two grass allergen extracts (timothy and orchard grass) to cause a skin reaction similar to histamine. Thirty-one adults with grass pollen allergies received skin prick tests with different concentrations. The goal was to improve all…

This study looked at 34 children with a narrow upper jaw (maxillary hypoplasia) who needed a rapid palatal expander. Researchers measured the electrical activity of chewing muscles before treatment, right after expansion, and 6 months later. The goal was to see if correcting the …

This study examined 69 children aged 6 to 14 to see if a deviated nasal septum (a crooked wall inside the nose) is linked to allergic rhinitis (hay fever). Researchers compared kids with and without the deviation using allergy tests, nasal samples, and quality-of-life questionnai…

This completed study tested whether a dissolved allergy tablet (Itulazax) can be used as a nasal spray to diagnose birch pollen allergy. 89 participants received either the dissolved tablet or a saltwater spray, and their nasal symptoms and airflow were measured. The goal was to …