New drug aims to restore lost smell in clinical trial

NCT ID NCT06019000

Completed Symptom relief Sponsor: Cyrano Therapeutics, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new drug called CYR-064 in 151 adults aged 18-70 who have a reduced sense of smell (hyposmia). The goal was to see if the drug is safe and if it can improve smell and taste over 24 weeks compared to a placebo. Participants had no other nasal issues like polyps or sinusitis.

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Conditions

The condition(s) this trial relates to.

anosmia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HYPOSMIA

Contacts and locations

Locations

Advanced ENT and Allergy

Louisville, Kentucky, 40220, United States
Centers for Advanced ENT

Baltimore, Maryland, 21204, United States
Charleston ENT and Allergy

North Charleston, South Carolina, 29406, United States
Colorado ENT & Allergy

Colorado Springs, Colorado, 80923, United States
ENTAAFL

Boca Raton, Florida, 33487, United States
ENTAAFL

Plantation, Florida, 33324, United States
ENTAAFL

Port Saint Lucie, Florida, 34952, United States
Ear Nose Throat & Allergy Associates

Puyallup, Washington, 98374, United States
Houston Methodist

Houston, Texas, 77030, United States
KU Medical Center-University of Kansas

Kansas City, Kansas, 66160-8500, United States
Medical University of South Carolina-MUSC

Charleston, South Carolina, 29425, United States
Rush University Medical Center

Chicago, Illinois, 60612, United States
Specialty Physician Associates

Bethlehem, Pennsylvania, 18017, United States
Tandem Clinical Research

Marrero, Louisiana, 70072, United States

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