Can a simple antiseptic rinse improve sinus surgery recovery?

NCT ID NCT07470242

Completed Disease control Sponsor: Pusan National University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether rinsing the nose with diluted povidone-iodine (a common antiseptic) after sinus surgery helps people with chronic sinusitis recover better than standard saline or mucomyst rinses. Forty-eight adults who had sinus surgery used one of the three rinses daily for three months. Researchers checked healing with a scope and tested hearing to see if the rinse caused any ear damage.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: povidone-iodine nasal irrigation
What this could lead to: If it works, this could offer a simple, low-cost option for improving sinus healing after surgery.
What could go wrong: This is a small, completed trial with only 48 participants, so results may not apply to everyone. There is also a risk of hearing damage (ototoxicity) with povidone-iodine.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CHRONIC RHINOSINUSITIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

chronic rhinosinusitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC RHINOSINUSITIS

Contacts and locations

Locations

Pusan National University Hospital

Pusan, 49241, South Korea

More trials for these conditions

Other studies related to the condition(s) this trial covers.