New antibody injection aims to tame stubborn sinusitis
NCT ID NCT06439381
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a drug called TQH2722, a lab-made antibody that blocks inflammation, for people with severe chronic sinusitis (with or without nasal polyps). About 120 adults who completed a prior TQH2722 study will receive either 300mg or 600mg injections over a long period. Researchers will track side effects and how well the drug controls sinus symptoms.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
TQH2722 injection (a lab-made antibody that blocks inflammation signals)
What this could lead to
If it works, this could provide a new long-term treatment option for people with severe chronic sinusitis, reducing symptoms and the need for surgery.
What could go wrong
This is an early Phase 2 trial with only 120 participants, so results may not apply to everyone. The drug could cause side effects or fail to show clear benefit over existing treatments.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Baotou Central Hospital
NOT_YET_RECRUITINGBaotou, Inner Mongolia, 014000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Beijing Tongren Hospital, Capital Medical University
RECRUITINGBeijing, Beijing Municipality, 100730, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Cangzhou Central Hospital
NOT_YET_RECRUITINGCangzhou, Heibei, 061017, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Chengdu Second People's Hospital
NOT_YET_RECRUITINGChengdu, Sichuan, 610021, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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First Hospital of Shangxi Medical University
NOT_YET_RECRUITINGTaiyuan, Shangxi, 030001, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Guangxi Medical University Cancer Hospital
NOT_YET_RECRUITINGNanning, Guangxi, 530021, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hebei Medical University Third Hospital
NOT_YET_RECRUITINGShijiazhuang, Hebei, 050000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Henan Provincial People's Hospital
NOT_YET_RECRUITINGZhengzhou, Henan, 450003, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Jilin Provincial People's Hospital
NOT_YET_RECRUITINGChangchun, Jilin, 130021, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Loudi Central Hospital
NOT_YET_RECRUITINGChangsha, Hunan, 417000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Nanjing Drum Tower Hospital
NOT_YET_RECRUITINGNanjing, Jiangsu, 210008, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Renji Hospital Shanghai Jiaotong University School of Medical
NOT_YET_RECRUITINGShanghai, Shanghai Municipality, 200127, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Renmin Hospital of Wuhan University Hubei General Hospital
NOT_YET_RECRUITINGWuhan, Hubei, 430060, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Shandong Second People's Hospital
NOT_YET_RECRUITINGJinan, Shandong, 250299, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Shengjing Hospital Affiliated to China Medical University
NOT_YET_RECRUITINGShenyang, Liaoning, 110004, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Taizhou central hospital(Taizhou university hospital)
NOT_YET_RECRUITINGTaizhou, Zhejiang, 318000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The Affiliated Hospital of Yanbian University
NOT_YET_RECRUITINGYanji, Jilin, 133002, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The Central Hospital of Shenyang Medical College
NOT_YET_RECRUITINGShenyang, Liaoning, 110075, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The First Affiliated Hospital of Xinjiang Medical University
NOT_YET_RECRUITINGÜrümqi, Xinjiang, 830011, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The First Hospital of China Medical University
NOT_YET_RECRUITINGShenyang, Liaoning, 110002, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The First People's Hospital of Foshan
NOT_YET_RECRUITINGFoshan, Guangdong, 528000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The Second People's Hospital of Shenzhen
NOT_YET_RECRUITINGShenzhen, Guangdong, 518035, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Union Hospital, Tongji Medical College, Huazhong University of science and technology
NOT_YET_RECRUITINGWuhan, Hubei, 430022, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Weihai Central Hospital
NOT_YET_RECRUITINGWeihai, Shandong, 264499, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Wenling First People's Hospital
NOT_YET_RECRUITINGWenling, Zhejiang, 317599, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Yantai Yuhuangding Hospital
NOT_YET_RECRUITINGYantai, Shandong, 264000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Zibo Central Hospital
NOT_YET_RECRUITINGZibo, Shandong, 255036, China
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Zibo Central Hospital
NOT_YET_RECRUITINGZibo, Shandong, 255036, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••