Melatonin may calm nerves before sinus surgery – study finds optimal dose
NCT ID NCT07550751
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested different doses of melatonin (3, 5, and 10 mg) compared to a placebo in 160 adults undergoing sinus surgery. The goal was to see which dose best reduces anxiety and pain while keeping heart rate and blood pressure stable. Results could help doctors choose the right melatonin dose for a smoother surgical experience.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Melatonin
- What this could lead to
- If successful, this could identify the best melatonin dose to reduce anxiety and improve comfort before sinus surgery.
- What could go wrong
- This is a small, completed Phase 4 trial. Melatonin is generally safe, but its effectiveness for sedation may vary and may not replace standard sedatives.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Aswan university hospitals
Aswān, Egypt
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Other studies related to the condition(s) this trial covers.
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