New hope for stuffy noses: drug shrinks polyps in rare disease

NCT ID NCT07592104

First seen May 19, 2026 · Last updated May 22, 2026 · Updated 1 time

Summary

This study looked at whether mepolizumab 300 mg can improve sinus symptoms in 52 adults with EGPA (a rare inflammatory disease) and severe, hard-to-control nasal polyps. Researchers measured changes in polyp size, quality of life, and smell function over 12 months. The goal was to see if the drug reduces the need for surgery or steroids.

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Contacts and locations

Locations

  • Fondazione Policlinico Universitario A. Gemelli IRCCS

    Roma, Roma, 00168, Italy

Conditions

Explore the condition pages connected to this study.