New hope for rare disease: drug trial aims to tame EGPA inflammation

NCT ID NCT06230354

First seen May 02, 2026 · Last updated May 15, 2026 · Updated 4 times

Summary

This study tests a drug called tezepelumab in 42 adults with EGPA, a rare disease that causes inflammation in blood vessels and organs. The goal is to see if the drug helps patients reach remission (no symptoms and low steroid use) after 24 weeks. The trial is already done enrolling and is now analyzing results.

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Contacts and locations

Locations

  • Aberdeen Royal Infirmary - NHS Grampian

    Aberdeen, AB25 2ZN, United Kingdom

  • Barts Health NHS Trust

    London, EC1A 7BE, United Kingdom

  • Cambridge University Hospitals NHS Foundation Trust

    Cambridge, CB2 0QQ, United Kingdom

  • Guy's Hospital - Guy's and St Thomas' NHS Foundation Trust

    London, SE1 9RT, United Kingdom

  • Imperial College Healthcare NHS Trust

    London, W2 1PG, United Kingdom

  • Leeds Teaching Hospitals NHS Trust

    Leeds, United Kingdom

  • Liverpool University Hospitals NHS Foundation Trust

    Liverpool, L7 8YE, United Kingdom

  • Royal Brompton Hospital - Guy's and St Thomas' NHS Foundation Trust

    London, SW3 6NP, United Kingdom

  • Royal Free London NHS Trust

    London, NW3 2QG, United Kingdom

  • Royal Infirmary of Edinburgh - NHS Lothian

    Edinburgh, United Kingdom

  • University Hospitals Birmingham NHS Foundation Trust

    Birmingham, B15 2GW, United Kingdom

  • University Hospitals of Leicester NHS Trust

    Leicester, LE3 9QP, United Kingdom

Conditions

Explore the condition pages connected to this study.