Can this antihistamine tablet ease Kids' constant stuffy noses?

NCT ID NCT01861522

Completed Symptom relief Sponsor: Tanabe Pharma Corporation Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether the drug TAU-284 (bepotastine besilate) can reduce sneezing, runny nose, and congestion in children aged 7 to 15 with perennial allergic rhinitis (year-round nasal allergies). In a double-blind, placebo-controlled design, 473 children took either the drug or a placebo twice daily for two weeks. The goal was to confirm the drug's superiority over placebo and check its safety.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: bepotastine besilate (antihistamine tablet)
What this could lead to: If it works, this could provide a proven option to ease sneezing, runny nose, and congestion in children with year-round allergies.
What could go wrong: This is a completed Phase 3 trial, but results may not show a big enough benefit over placebo. Also, the drug is already approved in some forms, so this is confirmatory, not a breakthrough.

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Conditions

The condition(s) this trial relates to.

perennial allergic rhinitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PERENNIAL ALLERGIC RHINITIS

Contacts and locations

Locations

Reserch site

Fukuoka, Japan
Reserch site

Toyama, Japan

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