New nasal nerve device shows promise for stuffy noses

NCT ID NCT06128200

First seen Jun 24, 2026 · Last updated Jun 24, 2026

Summary

This completed trial tested the NEUROMARK device, which uses radiofrequency to disrupt nerves in the nose, against a sham (fake) procedure in 132 adults with chronic rhinitis. The goal was to see if the device could reduce symptoms like runny nose and congestion by at least 30% after 90 days. Participants had moderate to severe symptoms for at least 6 months before joining.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Advanced ENT & Allergy

    Louisville, Kentucky, 40220, United States

  • Ascension St. Vincent

    Anderson, Indiana, 46016, United States

  • Bethlehem ENT

    Bethlehem, Pennsylvania, 18017, United States

  • Breathe Clear Institute

    Torrance, California, 90503, United States

  • Centers for Advanced ENT Care

    Baltimore, Maryland, 21204, United States

  • ENT & Allergy Associates

    Puyallup, Washington, 98374-1145, United States

  • ENT & Allergy Associates of Florida

    Boynton Beach, Florida, 33426, United States

  • ENT & Allergy Associates of Florida

    Port Saint Lucie, Florida, 34952, United States

  • East Alabama ENT

    Opelika, Alabama, 36801, United States

  • ExcelENT

    Homewood, Alabama, 35204, United States

  • Houston Methodist ENT Specialists

    Houston, Texas, 77030, United States

  • Kentuckiana

    Louisville, Kentucky, 40205, United States

  • Richmond ENT

    Richmond, Virginia, 23235, United States

  • Sacramento ENT

    Sacramento, California, 95815, United States

  • Sensa Health

    Los Angeles, California, 90006, United States

  • The ENT & Allergy Centers of Texas

    McKinney, Texas, 75708, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

NEUROMARK System (device that uses radiofrequency to disrupt posterior nasal nerves)

What this could lead to

If it works, this could offer a long-lasting, non-drug option to reduce runny nose and congestion in people with chronic rhinitis.

What could go wrong

This is a completed trial with 132 participants, but results are not yet widely confirmed. The procedure is invasive and may cause temporary discomfort or side effects like nosebleeds or pain.

Conditions

The condition(s) this trial relates to.

chronic rhinitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.