New nasal nerve device shows promise for stuffy noses

NCT ID NCT06128200

Completed Symptom relief Sponsor: Neurent Medical Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed trial tested the NEUROMARK device, which uses radiofrequency to disrupt nerves in the nose, against a sham (fake) procedure in 132 adults with chronic rhinitis. The goal was to see if the device could reduce symptoms like runny nose and congestion by at least 30% after 90 days. Participants had moderate to severe symptoms for at least 6 months before joining.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: NEUROMARK System (device that uses radiofrequency to disrupt posterior nasal nerves)
What this could lead to: If it works, this could offer a long-lasting, non-drug option to reduce runny nose and congestion in people with chronic rhinitis.
What could go wrong: This is a completed trial with 132 participants, but results are not yet widely confirmed. The procedure is invasive and may cause temporary discomfort or side effects like nosebleeds or pain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

chronic rhinitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC RHINITIS

Contacts and locations

Locations

Advanced ENT & Allergy

Louisville, Kentucky, 40220, United States
Ascension St. Vincent

Anderson, Indiana, 46016, United States
Bethlehem ENT

Bethlehem, Pennsylvania, 18017, United States
Breathe Clear Institute

Torrance, California, 90503, United States
Centers for Advanced ENT Care

Baltimore, Maryland, 21204, United States
ENT & Allergy Associates

Puyallup, Washington, 98374-1145, United States
ENT & Allergy Associates of Florida

Boynton Beach, Florida, 33426, United States
ENT & Allergy Associates of Florida

Port Saint Lucie, Florida, 34952, United States
East Alabama ENT

Opelika, Alabama, 36801, United States
ExcelENT

Homewood, Alabama, 35204, United States
Houston Methodist ENT Specialists

Houston, Texas, 77030, United States
Kentuckiana

Louisville, Kentucky, 40205, United States
Richmond ENT

Richmond, Virginia, 23235, United States
Sacramento ENT

Sacramento, California, 95815, United States
Sensa Health

Los Angeles, California, 90006, United States
The ENT & Allergy Centers of Texas

McKinney, Texas, 75708, United States

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