New device zaps nasal nerves to stop runny nose

NCT ID NCT05591989

Completed Disease control Sponsor: Neurent Medical Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a device called NEUROMARK in 80 adults with chronic rhinitis (long-term stuffy or runny nose). The device uses radiofrequency energy to disrupt nerves in the nose that trigger symptoms. The goal was to see if it safely reduces nasal symptoms like congestion and sneezing over 6 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: NEUROMARK System (a device that uses radiofrequency energy to disrupt posterior nasal nerves)
What this could lead to: If it works, this could offer a long-lasting, non-drug option to control chronic rhinitis symptoms.
What could go wrong: This was a small, single-arm study with no placebo group, so results may not be definitive. The procedure carries typical risks of nasal surgery, such as pain or bleeding.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

chronic rhinitis rhinitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC RHINITIS

Contacts and locations

Locations

Alabama Nasal and Sinus Center (Alabama Allergy)

Birmingham, Alabama, 35242, United States
Centers for Advanced ENT Care (CAdENT)

Baltimore, Maryland, 21204, United States
Colorado ENT

Colorado Springs, Colorado, 80923, United States
Ear Nose Throat & Allergy Associates

Seattle, Washington, 98374-1145, United States
New Orleans Sinus Center

Marrero, Louisiana, 70072, United States
Richmond ENT

Richmond, Virginia, 23235, United States
Rontal Clinics

Royal Oak, Michigan, 48073, United States
Sacramento ENT

California City, California, 95661, United States
Specialty Physician Associates

Bethlehem, Pennsylvania, 18017, United States
United Medical Doctors

Temecula, California, 92592, United States

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