Can a nerve block make sinus surgery less bloody?
NCT ID NCT03970655
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study tests whether adding epinephrine to a standard nerve block (pterygopalatine ganglion block) reduces bleeding during functional endoscopic sinus surgery (FESS) in people with chronic rhinosinusitis. Eighty adults undergoing bilateral FESS will receive the nerve block with epinephrine on one side and without on the other, and surgeons will rate bleeding using a standard scale. The goal is to see if this simple addition can improve surgical conditions.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
bupivacaine or ropivacaine with epinephrine plus dexamethasone
What this could lead to
If it works, this could lead to a simple way to reduce bleeding during sinus surgery, making the procedure safer and easier for surgeons.
What could go wrong
This is a small early-phase pilot study, so results may not be conclusive. The effect on bleeding might be small or not clinically meaningful.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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UF Health of University of Florida
Gainesville, Florida, 32610, United States