Could viruses and epigenetics be the hidden cause of chronic sinusitis?
NCT ID NCT05857228
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study investigates why some people develop chronic sinusitis with nasal polyps, focusing on how epigenetic changes and viruses might trigger the disease. Researchers will analyze tissue samples from 60 participants, including patients with active disease, those in remission, and healthy volunteers. The goal is to find new biomarkers and viral links that could lead to better treatments.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this study could identify new biomarkers and viral triggers for chronic sinusitis, pointing toward novel therapies.
- What could go wrong
- This is an observational study, not a treatment trial. It is small (60 participants) and early-stage, so findings may not lead to direct treatments.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CHUM
Montreal, Quebec, H2X 3E4, Canada
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