Could viruses and epigenetics be the hidden cause of chronic sinusitis?

NCT ID NCT05857228

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study investigates why some people develop chronic sinusitis with nasal polyps, focusing on how epigenetic changes and viruses might trigger the disease. Researchers will analyze tissue samples from 60 participants, including patients with active disease, those in remission, and healthy volunteers. The goal is to find new biomarkers and viral links that could lead to better treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could identify new biomarkers and viral triggers for chronic sinusitis, pointing toward novel therapies.

What could go wrong

This is an observational study, not a treatment trial. It is small (60 participants) and early-stage, so findings may not lead to direct treatments.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic rhinosinusitis disease Infections viral infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHUM

    Montreal, Quebec, H2X 3E4, Canada